Volume : 50 µg
Clone Number :
Aliases : 38 kDa FK506-binding protein antibody; 38 kDa FKBP antibody; 38kDa antibody; FK506 binding protein 8 antibody; FK506 binding protein 8, 38kDa antibody; FK506 binding protein, 38kDa antibody; FK506-binding protein 8 antibody; FKBP 38 antibody; FKBP-38 antibody; FKBP-8 antibody; Fkbp8 antibody; FKBP8_HUMAN antibody; FKBPR38 antibody; hFKBP38 antibody; Peptidyl-prolyl cis-trans isomerase FKBP8 antibody; PPIase FKBP8 antibody; Rotamase antibody; Sam11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14318
Immunogen : Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Constitutively inactive PPiase, which becomes active when bound to calmod µLin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and mod µLates its phosphorylation state. The BCL2/FKBP8/calmod µLin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the reg µLation of apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FKBP8
Research Areas : Cell biology; Signal transduction