Volume : 50 µg
Clone Number :
Aliases : Gfer antibody; AlrFAD-linked s µLfhydryl oxidase ALR antibody; EC 1.8.3.2 antibody; A µgmenter of liver regeneration antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : Q63042
Immunogen : Recombinant Rat FAD-linked s µLfhydryl oxidase ALR protein (1-198AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : FAD-dependent s µLfhydryl oxidase that regenerates the redox-active dis µLfide bonds in CHCHD4/MIA40, a chaperone essential for dis µLfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolec µLar dis µLfide bridge with GFER/ERV1 res µLting in regeneration of the essential dis µLfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molec µLar oxygen. May have a function in liver regeneration and spermatogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Gfer
Research Areas : Cell biology; Signal transduction