Biotinilated

Volume : 50 µg
Clone Number :
Aliases : Core histone macro H2A2.2 antibody; Core histone macro-H2A.2 antibody; Core histone macroH2A2.2 antibody; H2A histone family member Y2 antibody; H2AFY2 antibody; H2AW_HUMAN antibody; Histone macroH2A2 antibody; Macro H2A.2 antibody; Macro H2A2 antibody; MacroH2A.2 antibody; MacroH2A2 antibody; mH2A2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P0M6
Immunogen : Recombinant Human Core histone macro-H2A.2 protein (1-260AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2AFY2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : H2A histone family member X antibody; H2A histone family member X antibody; H2A.FX antibody; H2A.X antibody; H2a/x antibody; H2AFX antibody; H2AX antibody; H2AX_HUMAN antibody; Histone H2A.X antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16104
Immunogen : Recombinant Human Histone H2AX protein (12-141AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2AFX
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : H2AFV antibody; H2AV antibody; Histone H2A.V antibody; H2A.F/Z antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q71UI9
Immunogen : Recombinant Human Histone H2A.V protein (1-128AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2AFV
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : H2AFJ antibody; Histone H2A.J antibody; H2a/j antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BTM1
Immunogen : Recombinant Human Histone H2A.J protein (2-129AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2AFJ
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : H2AB1 antibody; H2AFB1 antibody; Histone H2A-Bbd type 1 antibody; H2A Barr body-deficient antibody; H2A.B antibody; H2A.Bbd antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P0C5Y9
Immunogen : Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2AFB1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : H2-K1 antibody; H2-K antibody; H-2 class I histocompatibility antigen antibody; K-D alpha chain antibody; H-2K(D) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P01902
Immunogen : Recombinant Mouse H-2 class I histocompatibility antigen, K-D alpha chain protein (22-305AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2-K1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : H2-D1 antibody; H-2 class I histocompatibility antigen antibody; D-D alpha chain antibody; H-2D(D) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P01900
Immunogen : Recombinant Mouse H-2 class I histocompatibility antigen, D-D alpha chain protein (25-311AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Involved in the presentation of foreign antigens to the immune system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : H2-D1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : GRAM_HUMAN antibody; Granzyme M (lymphocyte met ase 1) antibody; Granzyme M antibody; GranzymeM antibody; GZM M antibody; Gzmm antibody; HU Met 1 antibody; HU-Met-1 antibody; LMET 1 antibody; LMET1 antibody; Lymphocyte met ase 1 antibody; MET 1 antibody; Met 1 serine protease antibody; Met ase antibody; Met-1 serine protease antibody; Met-ase antibody; MET1 antibody; Met1 serine protease antibody; Natural killer cell gran µLar protease antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51124
Immunogen : Recombinant Human Granzyme M protein (98-243AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tub µLins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GZMM
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Fragmentin 3 antibody; Fragmentin-3 antibody; Fragmentin3 antibody; GRAK_HUMAN antibody; Granzyme 3 antibody; granzyme K (granzyme 3; tryptase II) antibody; granzyme K (serine protease; granzyme 3; tryptase II) antibody; Granzyme K antibody; Granzyme K precursor antibody; Granzyme-3 antibody; Granzyme3 antibody; GranzymeK antibody; GZMK antibody; NK TRYP 2 antibody; NK TRYP2 antibody; NK tryptase 2 antibody; NK-TRYP-2 antibody; NK-tryptase-2 antibody; NKTRYP2 antibody; Serine protease granzyme 3 antibody; TRYP 2 antibody; TRYP2 antibody; Tryptase II antibody; TryptaseII antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49863
Immunogen : Recombinant Human Granzyme K protein (27-264AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : serine-type peptidase activity
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GZMK
Research Areas : Cell biology; Immunology

Volume : 50 µg
Clone Number :
Aliases : C11 antibody; Cathepsin G like 1 antibody; Cathepsin G-like 1 antibody; CCPI antibody; CGL 1 antibody; CGL1 antibody; CSP B antibody; CSPB antibody; CTLA 1 antibody; CTLA-1 antibody; CTLA1 antibody; CTSGL1 antibody; Cytotoxic serine protease B antibody; Cytotoxic T lymphocyte associated serine esterase 1 antibody; Cytotoxic T lymphocyte proteinase 2 antibody; Cytotoxic T-lymphocyte proteinase 2 antibody; Fragmentin 2 antibody; Fragmentin-2 antibody; GRAB_HUMAN antibody; Granzyme 2 antibody; Granzyme B (granzyme 2; cytotoxic T lymphocyte associated serine esterase 1) antibody; Granzyme B antibody; Granzyme-2 antibody; GranzymeB antibody; GRB antibody; Gzmb antibody; Hlp antibody; Human lymphocyte protein antibody; Lymphocyte protease antibody; Protease; serine; B antibody; SECT antibody; T cell serine protease 1 3E antibody; T cell serine protease 1-3E antibody; T-cell serine protease 1-3E antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10144
Immunogen : Recombinant Human Granzyme B protein (21-247AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GZMB
Research Areas : Cell biology; Immunology

Volume : 50 µg
Clone Number :
Aliases : Gzma antibody; Ctla-3 antibody; Ctla3 antibody; Mtsp-1 antibody; Granzyme A antibody; EC 3.4.21.78 antibody; Autocrine thymic lymphoma granzyme-like serine protease antibody; CTLA-3 antibody; Fragmentin-1 antibody; T cell-specific serine protease 1 antibody; TSP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P11032
Immunogen : Recombinant Mouse Granzyme A protein (29-260AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Abundant protease in the cytosolic gran µLes of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell thro µgh the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Gzma
Research Areas : Others