Volume : 50 µg
Clone Number :
Aliases : G protein coupled receptor 75 antibody; GPR chr2 antibody; Gpr75 antibody; GPR75_HUMAN antibody; GPRchr2 antibody; OTTHUMP00000159608 antibody; Probable G protein coupled receptor 75 antibody; Probable G-protein coupled receptor 75 antibody; WI 31133 antibody; WI31133 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95800
Immunogen : Recombinant Human Probable G-protein coupled receptor 75 protein (372-540AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stim µLates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival thro µgh activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also reg µLate ins µLin secretion by pancreatic islet cells thro µgh activation of this receptor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GPR75
Research Areas : Signal transduction