Volume : 50 µg
Clone Number :
Aliases : IFNT1 antibody; Interferon tau-1 antibody; IFN-tau-1 antibody; Antiluteolysin antibody; Trophoblast antiluteolytic protein antibody; Trophoblast protein 1 antibody; TP-1 antibody; Trophoblastin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bos taurus (Bovine)
UniProt ID : P15696
Immunogen : Recombinant Bovine Interferon tau-1 protein (24-195AA)
Raised in : Rabbit
Species Reactivity : Bovine
Tested Applications : ELISA
Background : Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This res µLts in the suppression of the p µLsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stim µLates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays partic µLarly high antiviral and antiproliferative potency concurrently with partic µLar weak cytotoxicity, high antiluteolytic activity and immunomod µLatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFNT1
Research Areas : Others