Biotinilated

Volume : 50 µL
Clone Number :
Aliases : JRK antibody; JH8 antibody; Jerky protein homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75564
Immunogen : Peptide sequence from Human Jerky protein homolog protein (465-483AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May bind DNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JRK
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Androgen reg µLated protein 2 antibody; Androgen-reg µLated protein 2 antibody; ARM2 antibody; Hematological and neurological expressed 1 antibody; Hematological and neurological expressed 1 protein antibody; HN1 antibody; HN1_HUMAN antibody; HN1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UK76
Immunogen : Recombinant Human Jupiter microtub µLe associated homolog 1 protein (2-154AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JPT1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DKFZp762L0313 antibody; JP 1 antibody; JP-1 antibody; JP1 antibody; JPH 1 antibody; JPH1 antibody; JPH1_HUMAN antibody; Junctophilin 1 antibody; Junctophilin type 1 antibody; Junctophilin type1 antibody; Junctophilin-1 antibody; Junctophilin1 antibody; Mits µgumin 72 antibody; Mits µgumin72 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9HDC5
Immunogen : Recombinant Human Junctophilin-1 protein (431-546AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic retic µLum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracell µLar calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tub µLe (transverse-tub µLe) and SR (sarcoplasmic retic µLum) membranes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JPH1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : FLJ37870 antibody; Jmy antibody; JMY protein antibody; JMY_HUMAN antibody; junction mediating and reg µLatory protein antibody; Junction mediating and reg µLatory protein p53 cofactor antibody; Junction-mediating and -reg µLatory protein antibody; MGC163496 antibody; OTTHUMP00000161976 antibody; WAS protein homology region 2 domain containing 1-like 3 antibody; WHDC1L3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N9B5
Immunogen : Recombinant Human Junction-mediating and -reg µLatory protein (708-848AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic reg µLator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, s µggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are reg µLated via its subcell µLar location (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JMY
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : JHD2C_HUMAN antibody; Jmjd1c antibody; Jumonji domain containing 1C antibody; Jumonji domain-containing protein 1C antibody; Probable JmjC domain-containing histone demethylation protein 2C antibody; Thryoid receptor interacting protein antibody; Thyroid receptor-interacting protein 8 antibody; TR-interacting protein 8 antibody; TRIP-8 antibody; TRIP8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15652
Immunogen : Recombinant Human Probable JmjC domain-containing histone demethylation protein 2C protein (539-648AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable histone demethylase that specifically demethylates \\\'Lys-9\\\' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JMJD1C
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : JARD2 antibody; JARD2_HUMAN antibody; JARID2 antibody; JMJ antibody; Jumonji AT rich interactive domain 2 antibody; Jumonji homolog antibody; Jumonji like protein antibody; Jumonji protein antibody; Jumonji/ARID domain containing protein 2 antibody; Jumonji/ARID domain-containing protein 2 antibody; Protein Jumonji antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92833
Immunogen : Recombinant Human Protein Jumonji protein (1-159AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by mod µLating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but reg µLates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of \\\'Lys-27\\\' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of \\\'Lys-9\\\' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative reg µLation of cell proliferation signaling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JARID2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 50 µg
Clone Number :
Aliases : FLJ14529 antibody; JAM 2 antibody; JAM 3 antibody; JAM C antibody; JAM-2 antibody; JAM-3 antibody; JAM-C antibody; JAM2 antibody; Jam3 antibody; JAM3_HUMAN antibody; JAMC antibody; Junctional adhesion molec µLe 3 antibody; Junctional adhesion molec µLe 3 precursor antibody; Junctional adhesion molec µLe C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BX67
Immunogen : Recombinant Human Junctional adhesion molec µLe C protein (119-235AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Participates in cell-cell adhesion. It is a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the reg µLation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JAM3
Research Areas : Cardiovasc µLar; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C21orf43 antibody; CD 322 antibody; CD322 antibody; CD322 antigen antibody; JAM 2 antibody; JAM B antibody; JAM IT/VE JAM antibody; JAM; vasc µLar endothelial antibody; JAM-2 antibody; JAM-B antibody; JAM2 antibody; JAM2_HUMAN antibody; JAMB antibody; Jcam2 antibody; Junction adhesion molec µLe 2 antibody; Junction adhesion molec µLe B antibody; Junctional adhesion molec µLe 2 antibody; Junctional adhesion molec µLe B antibody; PRO 245 antibody; PRO245 antibody; Vasc µLar endothelial junction associated molec µLe antibody; Vasc µLar endothelial junction-associated molec µLe antibody; VE JAM antibody; VE-JAM antibody; VEJAM antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P57087
Immunogen : Recombinant Human Junctional adhesion molec µLe B protein (29-238AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JAM2
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EC 2.7.10.2 antibody; JAK 3 antibody; JAK L antibody; JAK-3 antibody; Jak3 antibody; JAK3 HUMAN antibody; JAK3_HUMAN antibody; JAKL antibody; Janus kinase 3 (a protein tyrosine kinase; leukocyte) antibody; Janus kinase 3 antibody; Janus Kinase3 antibody; L JAK antibody; L-JAK antibody; Leukocyte janus kinase antibody; LJAK antibody; Protein tyrosine kinase leukocyte antibody; Tyrosine protein kinase JAK3 antibody; Tyrosine-protein kinase JAK3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52333
Immunogen : Recombinant Human Tyrosine-protein kinase JAK3 protein (351-614AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, upon IL2R activation by IL2, JAK1 and JAK3 molec µLes bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. Then, STAT5A AND STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3. Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JAK3
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : JAK 2 antibody; JAK-2 antibody; JAK2 antibody; JAK2_HUMAN antibody; Janus Activating Kinase 2 antibody; Janus kinase 2 (a protein tyrosine kinase) antibody; Janus kinase 2 antibody; JTK 10 antibody; JTK10 antibody; kinase Jak2 antibody; OTTHUMP00000043260 antibody; THCYT3 antibody; Tyrosine protein kinase JAK2 antibody; Tyrosine-protein kinase JAK2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60674
Immunogen : Recombinant Human Tyrosine-protein kinase JAK2 protein (752-1132AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and m µLtiple interleukins. Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stim µLation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. Once activated, dimerized STAT5 translocates into the nucleus and promotes the transcription of several essential genes involved in the mod µLation of erythropoiesis. In addition, JAK2 mediates angiotensin-2-induced ARHGEF1 phosphorylation. Plays a role in cell cycle by phosphorylating CDKN1B. Cooperates with TEC thro µgh reciprocal phosphorylation to mediate cytokine-driven activation of FOS transcription. In the nucleus, plays a key role in chromatin by specifically mediating phosphorylation of \'Tyr-41\' of histone H3 (H3Y41ph), a specific tag that promotes exclusion of CBX5 (HP1 alpha) from chromatin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JAK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ14602 antibody; GL009 antibody; JAGN 1 antibody; JAGN1 antibody; JAGN1_HUMAN antibody; Jagunal homolog 1 antibody; Jagunal; drosophila; homolog of; 1 antibody; MGC112769 antibody; Protein jagunal homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N5M9
Immunogen : Recombinant Human Protein jagunal homolog 1 protein (1-39AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Endoplasmic retic µLum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracell µLar protein transport. Acts as a reg µLator of neutrophil function, probably via its role in vesicle-mediated transport : required for defense against fungal pathogens and for gran µLocyte colony-stim µLating factor (GM-CSF) signaling pathway; possibly by reg µLating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : JAGN1
Research Areas : Tags & Cell Markers