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Biotinilated

ITGB2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody; Leukocyte cell adhesion molec µLe CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05107
Immunogen : Recombinant Human Integrin beta-2 protein (37-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed : 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed : 11812992). Triggers neutrophil transmigration during lung injury thro µgh PTK2B/PYK2-mediated activation (PubMed : 18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed : 23775590).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB2
Research Areas : Immunology; Signal transduction; Stem cells
0.01 0.01 USD
ITGB1BP2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKP3
Immunogen : Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role during maturation and/or organization of muscles cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP2
Research Areas : Cardiovasc µLar; Signal transduction
0.01 0.01 USD
ITGB1BP1 Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : ITGB1BP1 antibody; ICAP1Integrin beta-1-binding protein 1 antibody; Integrin cytoplasmic domain-associated protein 1 antibody; ICAP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14713
Immunogen : Recombinant Human Integrin beta-1-binding protein 1 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key reg µLator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stim µLates cell µLar proliferation in a fibronectin-dependent manner. Involved in the reg µLation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1 and hence stim µLates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner. Acts as a guanine nucleotide dissociation inhibitor (GDI) by reg µLating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin. Stim µLates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool. Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin. Plays a role in bone mineralization at a late stage of osteoblast differentiation; mod µLates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis. Plays a role in blood vessel development; acts as a negative reg µLator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation thro µgh activation of the Notch signaling pathway. Promotes transcriptional activity of the MYC promoter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP1
Research Areas : Signal transduction
0.01 0.01 USD
Itgb1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Itgb1 antibody; Integrin beta-1 antibody; Fibronectin receptor subunit beta antibody; VLA-4 subunit beta antibody; CD antigen CD29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P09055
Immunogen : Recombinant Mouse Integrin beta-1 protein (21-728AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Integrins alpha-1/beta-1 alpha-2/beta-1 alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1 alpha-3/beta-1 alpha-4/beta-1 alpha-5/beta-1 alpha-8/beta-1 alpha-10/beta-1 alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1 alpha-2/beta-1 alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, reg µLates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction thro µgh the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nod µLes. May be involved in up-reg µLation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1 serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successf µL completion of cytokinesis. ITGA4 : ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (By similarity). ITGA4 : ITGB1 and ITGA5 : ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Itgb1
Research Areas : Neuroscience; Developmental biology; Microbiology; Signal transduction; Stem cells
0.01 0.01 USD
ITGAV Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06756
Immunogen : Recombinant Human Integrin alpha-V protein (775-885AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV : ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed : 23125415). ITGAV : ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGAV : ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed : 18441324). ITGAV : ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 19578119). ITGAV : ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGAV : ITGB3 and ITGAV : ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAV
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells
0.01 0.01 USD
ITGAM Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : antigen CD11b (p170) antibody; Antigen CD11b p170 antibody; CD11 antigen like family member B antibody; CD11 antigen-like family member B antibody; CD11b antibody; CD11b/CD18 antibody; CD49d antibody; Cell surface glycoprotein MAC-1 subunit alpha antibody; Complement component 3 receptor 3 subunit antibody; Complement Component Receptor 3 Alpha antibody; Complement receptor type 3 antibody; Complement receptor type 3, alpha subunit antibody; CR 3 alpha chain (CR3A) antibody; CR 3 alpha chain antibody; CR-3 alpha chain antibody; CR3 antibody; CR3A antibody; F730045J24Rik antibody; Integrin Alpha M antibody; Integrin alpha M chain antibody; Integrin alpha-M antibody; Integrin beta 2 alpha subunit antibody; Integrin subunit alpha M antibody; integrin, alpha M (complement component 3 receptor 3 subunit) antibody; ITAM_HUMAN antibody; ITGAM antibody; Leukocyte adhesion receptor MO1 antibody; Ly-40 antibody; MAC 1 antibody; Mac-1a antibody; MAC1 antibody; Mac1 alpha subunit antibody; MAC1A antibody; Macrophage antigen alpha polypeptide antibody; MGC117044 antibody; Mo1 antibody; Mo1 alpha subunit antibody; MO1A antibody; Neutrophil adherence receptor alpha M subunit antibody; Neutrophil adherence receptor antibody; SLEB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11215
Immunogen : Recombinant Human Integrin alpha-M protein (46-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and gran µLocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience; Tags & Cell Markers; Signal transduction; Stem cells
0.01 0.01 USD
ITGAL Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Antigen CD11A (p180); lymphocyte function associated antigen 1; alpha polypeptide antibody; CD11 antigen-like family member A antibody; CD11a antibody; CD18 antibody; CR3 antibody; Integrin alpha-L antibody; Integrin beta 2 antibody; Integrin gene promoter antibody; ITAL_HUMAN antibody; Itgal antibody; ITGAM antibody; ITGB2 antibody; LAD antibody; Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody; Leukocyte function-associated molec µLe 1 alpha chain antibody; LFA 1 alpha antibody; LFA 1 antibody; LFA-1A antibody; LFA1 antibody; LFA1A antibody; Lymphocyte function associated antigen 1 antibody; MAC1 antibody; MFI7 antibody; MO1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20701
Immunogen : Recombinant Human Integrin alpha-L protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by gran µLocytes and monocytes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology; Signal transduction; Stem cells
0.01 0.01 USD
ITGA8 Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : Integrin alpha 8 antibody; Integrin alpha-8 heavy chain antibody; Integrin alpha-8 light chain antibody; ITA8_HUMAN antibody; ITGA 8 antibody; ITGA8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53708
Immunogen : Peptide sequence from Human Integrin alpha-8 protein (114-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by reg µLating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1 SPP1 TGFB1 TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and reg µLates neurite outgrowth of sensory and motor neurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA8
Research Areas : Signal transduction
0.01 0.01 USD
ITGA7 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : alpha 7 antibody; FLJ25220 antibody; Integrin alpha 7 antibody; Integrin alpha 7 chain antibody; Integrin alpha 7 heavy chain antibody; Integrin alpha 7 light chain antibody; Integrin alpha-7 70 kDa form antibody; ITA7_HUMAN antibody; ITGA 7 antibody; Itga7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13683
Immunogen : Recombinant Human Integrin alpha-7 protein (175-283AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and ad µLt myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vasc µLar smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA7
Research Areas : Cancer; Cardiovasc µLar; Signal transduction
0.01 0.01 USD
ITGA6 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Alpha6p antibody; CD49 antigen-like family member F antibody; CD49f antibody; Integrin alpha6B antibody; Integrin, alpha 6 antibody; ITA6_HUMAN antibody; ITGA6 antibody; ITGA6B antibody; Processed integrin alpha-6 antibody; VLA 6 antibody; VLA-6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P23229
Immunogen : Recombinant Human Integrin alpha-6 protein (625-866AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA6
Research Areas : Developmental biology; Signal transduction; Stem cells
0.01 0.01 USD
ITGA5 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08648
Immunogen : Recombinant Human Integrin alpha-5 protein (220-472AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGA5 : ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA5
Research Areas : Signal transduction; Stem cells
0.01 0.01 USD