Biotinilated

Volume : 50 µg
Clone Number :
Aliases : h-warts antibody; Large tumor suppressor homolog 1 antibody; LATS large tumor suppressor homolog 1 antibody; LATS1 antibody; LATS1_HUMAN antibody; Serine threonine protein kinase LATS1 antibody; Serine/threonine-protein kinase LATS1 antibody; WARTS antibody; WARTS protein kinase antibody; wts antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95835
Immunogen : Recombinant Human Serine/threonine-protein kinase LATS1 protein (1-280AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Negative reg µLator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ Volume control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1 in complex with its reg µLatory protein SAV1 phosphorylates and activates LATS1/2 in complex with its reg µLatory protein MOB1 which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1 inhibits its translocation into the nucleus to reg µLate cell µLar genes important for cell proliferation, cell death, and cell migration. Acts as a tumor suppressor which plays a critical role in maintenance of ploidy thro µgh its actions in both mitotic progression and the G1 tetraploidy checkpoint. Negatively reg µLates G2/M transition by down-reg µLating CDK1 kinase activity. Involved in the control of p53 expression. Affects cytokinesis by reg µLating actin polymerization thro µgh negative mod µLation of LIMK1. May also play a role in endocrine function.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LATS1
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : LASP 1 antibody; LASP-1 antibody; LASP1 antibody; LASP1_HUMAN antibody; LIM and SH3 domain protein 1 antibody; LIM and SH3 protein 1 antibody; Metastatic lymph node gene 50 protein antibody; MLN 50 antibody; MLN50 antibody; OTTHUMP00000164238 antibody; OTTHUMP00000164239 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14847
Immunogen : Recombinant Human LIM and SH3 domain protein 1 protein (128-252AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays an important role in the reg µLation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to reg µLate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LASP1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : lasA antibody; PA1871Protease LasA antibody; EC 3.4.24.- antibody; Staphylolytic protease antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Pseudomonas aer µginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
UniProt ID : P14789
Immunogen : Recombinant Pseudomonas aer µginosa Protease LasA protein (237-418AA)
Raised in : Rabbit
Species Reactivity : Pseudomonas aer µginosa
Tested Applications : ELISA
Background : Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed : 11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed : 2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aer µginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate (PubMed : 20026068).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : lasA
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : dJ475B7.2 antibody; FLJ12525 antibody; FLJ30133 antibody; FLJ45274 antibody; LAS1 like (S. cerevisiae) antibody; Las1 like antibody; LAS1L antibody; LAS1L_HUMAN antibody; Protein LAS1 homolog antibody; Ribosomal biogenesis protein LAS1L antibody; RP3 475B7.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y4W2
Immunogen : Recombinant Human Ribosomal biogenesis protein LAS1L protein (490-565AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAS1L
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Larval cuticle protein A1A antibody; TM-LCP A1A antibody; TM-A1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Tenebrio molitor (Yellow mealworm beetle)
UniProt ID : P80681
Immunogen : Recombinant Tenebrio molitor Larval cuticle protein A1A protein (1-174AA)
Raised in : Rabbit
Species Reactivity : Tenebrio molitor
Tested Applications : ELISA
Background : Component of the cuticle of the larva of Tenebrio molitor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : cytoplasmic antibody; Cytoplasmic leucyl tRNA synthetase antibody; Cytosolic leucyl tRNA synthetase antibody; FLJ10595 antibody; FLJ21788 antibody; hr025Cl antibody; HSPC 192 antibody; HSPC192 antibody; KIAA1352 antibody; LARS 1 antibody; Lars antibody; LARS1 antibody; Leucine translase antibody; Leucine tRNA ligase antibody; Leucine--tRNA ligase antibody; Leucyl tRNA synthetase cytoplasmic antibody; Leucyl-tRNA synthetase antibody; LeuRS antibody; LEUS antibody; LRS antibody; PIG 44 antibody; PIG44 antibody; Proliferation inducing gene 44 antibody; RNTLS antibody; SYLC_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2J5
Immunogen : Recombinant Human Leucine--tRNA ligase, cytoplasmic protein (614-892AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction : the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LARS
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DKFZp564K112 antibody; HDCMA18P antibody; La related protein 7 antibody; La ribonucleoprotein domain family member 7 antibody; La ribonucleoprotein domain family member 7 antibody; La-related protein 7 antibody; LARP 7 antibody; larp7 antibody; LARP7_HUMAN antibody; MGC104360 antibody; P TEFb interaction protein for 7SK stability antibody; P-TEFb-interaction protein for 7SK stability antibody; PIP7S antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q4G0J3
Immunogen : Recombinant Human La-related protein 7 protein (409-471AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Negative transcriptional reg µLator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LARP7
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Acheron antibody; Achn antibody; FLJ11196 antibody; La ribonucleoprotein domain family member 6 antibody; La-related protein 6 antibody; LARP6 antibody; LARP6_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BRS8
Immunogen : Recombinant Human La-related protein 6 protein (294-453AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs thro µgh high-affinity binding of a stem-loop structure in their 5\' UTR. This reg µLation requires VIM and MYH10 filaments, and the helicase DHX9.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LARP6
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : LARP1B antibody; LARP2 antibody; La-related protein 1B antibody; La ribonucleoprotein domain family member 1B antibody; La ribonucleoprotein domain family member 2 antibody; La-related protein 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q659C4
Immunogen : Recombinant Human La-related protein 1B protein (1-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LARP1B
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : LAPTM5 antibody; KIAA0085 antibody; Lysosomal-associated transmembrane protein 5 antibody; Lysosomal-associated m µLtitransmembrane protein 5 antibody; Retinoic acid-inducible E3 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13571
Immunogen : Recombinant Human Lysosomal-associated transmembrane protein 5 protein (205-262AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May have a special functional role during embryogenesis and in ad µLt hematopoietic cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAPTM5
Research Areas : Developmental biology

Volume : 50 µg
Clone Number :
Aliases : LAPTM4B antibody; PSEC0001 antibody; Lysosomal-associated transmembrane protein 4B antibody; Lysosome-associated transmembrane protein 4-beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86VI4
Immunogen : Recombinant Human Lysosomal-associated transmembrane protein 4B protein (174-226AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for optimal lysosomal function (PubMed : 21224396). Blocks EGF-stim µLated EGFR intraluminal sorting and degradation. Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, reg µLates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation (PubMed : 25588945). Recruits SLC3A2 and SLC7A5 (the Leu transporter) to the lysosome, promoting entry of leucine and other essential amino acid (EAA) into the lysosome, stim µLating activation of proton-transporting vacuolar (V)-ATPase protein pump (V-ATPase) and hence mTORC1 activation (PubMed : 25998567). Plays a role as negative reg µLator of TGFB1 production in reg µLatory T cells (PubMed : 26126825). Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways (PubMed : 26280656).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAPTM4B
Research Areas : Cancer