FITC

Volume : 50 µg
Clone Number :
Aliases : C1orf136 antibody; DISC1 antibody; DISC1_HUMAN antibody; Disrupted in schizophrenia 1 antibody; Disrupted in schizophrenia 1 protein antibody; KIAA0457 antibody; RP4-730B13.1 antibody; SCZD9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NRI5
Immunogen : Recombinant Human Disrupted in schizophrenia 1 protein (99-325AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the reg µLation of m µLtiple aspects of embryonic and ad µLt neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the ad µLt dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive reg µLator by mod µLating GSK3B activity and CTNNB1 abundance. Plays a role as a mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Reg µLates the migration of early-born gran µLe cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtub µLe network formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DISC1
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : DI3L2_HUMAN antibody; DIS3 L2 antibody; DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody; DIS3 mitotic control homolog like 2 antibody; DIS3-like exonuclease 2 antibody; Dis3l2 antibody; FLJ36974 antibody; MGC42174 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IYB7
Immunogen : Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively reg µLates cell proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIS3L2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DIS3L antibody; DIS3L1 antibody; KIAA1955DIS3-like exonuclease 1 antibody; EC 3.1.13.- antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TF46
Immunogen : Recombinant Human DIS3-like exonuclease 1 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIS3L
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 2810028N01Rik antibody; bA555G22 antibody; Dis3 antibody; DIS3 homolog; exosome endoribonuclease and 3'-5' exoribonuclease antibody; DIS3 mitotic control homolog (S. cerevisiae) antibody; DIS3 mitotic control homolog antibody; DIS3 mitotic control; S. cerevisiae; homolog of antibody; dis3p antibody; EXOSC11 antibody; Exosome complex exonuclease RRP44 antibody; exosome component 11 antibody; KIAA1008 antibody; Mitotic control protein dis3 homolog antibody; Protein DIS3 homolog antibody; Ribosomal RNA processing protein 44 antibody; Ribosomal RNA processing protein 44; S. cerevisiae; homolog of antibody; Ribosomal RNA-processing protein 44 antibody; RP11-342J4.3 antibody; RRP44 antibody; RRP44_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2L1
Immunogen : Recombinant Human Exosome complex exonuclease RRP44 protein (30-187AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. DIS3 has both 3\'-5\' exonuclease and endonuclease activities.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIS3
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : DIRC1Disrupted in renal carcinoma protein 1 antibody; Disrupted in renal cancer protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q969H9
Immunogen : Recombinant Human Disrupted in renal carcinoma protein 1 protein (1-104AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIRC1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DIRAS1 antibody; GBTS1 antibody; RIGGTP-binding protein Di-Ras1 antibody; Distinct subgroup of the Ras family member 1 antibody; Ras-related inhibitor of cell growth antibody; Rig antibody; Small GTP-binding tumor suppressor 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95057
Immunogen : Recombinant Human GTP-binding protein Di-Ras1 protein (1-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Displays low GTPase activity and exists predominantly in the GTP-bound form.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIRAS1
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DIP2A antibody; C21orf106 antibody; DIP2 antibody; KIAA0184Disco-interacting protein 2 homolog A antibody; DIP2 homolog A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14689
Immunogen : Recombinant Human Disco-interacting protein 2 homolog A protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May provide positional cues for axon pathfinding and patterning in the central nervous system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIP2A
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 5DIII antibody; D3 antibody; Deiodinase iodothyronine type 3 antibody; Deiodinase iodothyronine type III antibody; Dio 3 antibody; Dio3 antibody; DIOIII antibody; IOD3_HUMAN antibody; Iodothyronine deiodinase placental type antibody; MGC124117 antibody; MGC124118 antibody; Thyroxine deiodinase type III antibody; Thyroxine deiodinase type III (selenoprotein) antibody; TXDI3 antibody; Type 3 DI antibody; Type 3 iodothyronine selenodeiodinase antibody; Type III 5' deiodinase antibody; Type III iodothyronine deiodinase antibody; Type-III 5''-deiodinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55073
Immunogen : Recombinant Human Thyroxine 5-deiodinase protein (50-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Responsible for the deiodination of T4 (3,5,3\',5\'-tetraiodothyronine) into RT3 (3,3\',5\'-triiodothyronine) and of T3 (3,5,3\'-triiodothyronine) into T2 (3,3\'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to ad µLt levels of thyroid hormones. Can reg µLate circ µLating fetal thyroid hormone concentrations thro µghout gestation. Essential role for reg µLation of thyroid hormone inactivation during embryological development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIO3
Research Areas : Neuroscience; Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 5DII antibody; D2 antibody; Deiodinase, iodothyronine, type II antibody; DIO2 antibody; DIOII antibody; EC 1.97.1.10 antibody; IOD2_HUMAN antibody; ITDI2 antibody; SelY antibody; Thyroxine deiodinase, type II antibody; TXDI2 antibody; Type 2 DI antibody; Type 2 iodothyronine deiodinase antibody; Type II 5' deiodinase antibody; Type II iodothyronine deiodinase antibody; Type-II 5''-deiodinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92813
Immunogen : Recombinant Human Type II iodothyronine deiodinase protein (74-222AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Responsible for the deiodination of T4 (3,5,3\',5\'-tetraiodothyronine) into T3 (3,5,3\'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIO2
Research Areas : Neuroscience; Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DIO1 antibody; ITDI1 antibody; TXDI1 antibody; Type I iodothyronine deiodinase antibody; EC 1.21.99.4 antibody; 5DI antibody; DIOI antibody; Type 1 DI antibody; Type-I 5'-deiodinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49895
Immunogen : Recombinant Human Type I iodothyronine deiodinase protein (34-249AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Responsible for the deiodination of T4 (3,5,3\',5\'-tetraiodothyronine) into T3 (3,5,3\'-triiodothyronine) and of T3 into T2 (3,3\'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIO1
Research Areas : Neuroscience; Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase antibody; 18S rRNA dimethylase antibody; DIM1 antibody; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) antibody; DIM1 dimethyladenosine transferase 1 homolog antibody; DIM1 dimethyladenosine transferase 1 like antibody; DIM1 dimethyladenosine transferase 1-like antibody; Dimethyladenosine transferase antibody; DIMT1 antibody; DIMT1_HUMAN antibody; DIMT1L antibody; HSA9761 antibody; HUSSY5 antibody; N''-adenosyl(rRNA) dimethyltransferase antibody; Probable 18S rRNA (adenine(1779) N(6)/adenine(1780) N(6)) dimethyltransferase antibody; Probable 18S rRNA dimethylase antibody; Probable dimethyladenosine transferase antibody; Probable S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase antibody; S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase antibody; S-adenosylmethionine-6-N'' antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UNQ2
Immunogen : Recombinant Human Probable dimethyladenosine transferase protein (1-313AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : pecifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3\'-end of 18S rRNA in the 40S particle.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIMT1
Research Areas : Epigenetics and Nuclear Signaling