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FITC

Conjugated antibodies for Flow Cytometry of Facs instruments BD FACS Calibur: Equipped with a 488 nm blue laser, suitable for FITC excitation.

BD LSR II: Configurable with up to four lasers, including a 488 nm blue laser for FITC detection.
 
BD FACS Canto II: Features a 488 nm blue laser, optimized for FITC detection with a sensitivity of <100 MESF.
  

BD LSR Fortessa: High-end analyzer configurable with multiple lasers, including a 488 nm blue laser for FITC detection.

BD FACS Symphony A5: Advanced analyzer with customizable laser configurations, supporting FITC detection.

BD FACS Melody: User-friendly cell sorter with a 488 nm blue laser, suitable for FITC-labeled samples.
EPHA5 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Brain-specific kinase antibody; bsk antibody; CEK 7 antibody; Eck like sequence 1 antibody; EHK 1 antibody; EHK-1 antibody; EK7 antibody; Els 1 antibody; EPH homology kinase 1 antibody; EPH-like kinase 7 antibody; EPHA5 antibody; EPHA5_HUMAN antibody; Ephrin type A receptor 5 antibody; Ephrin type-A receptor 5 antibody; HEK 7 antibody; hEK7 antibody; Receptor protein tyrosine kinase HEK 7 antibody; Rek 7 antibody; TYRO 4 antibody; Tyrosine protein kinase receptor EHK 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54756
Immunogen : Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molec µLe during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in ad µLt brain thro µgh reg µLation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to reg µLate glucose-stim µLated ins µLin secretion (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPHA5
Research Areas : Neuroscience; Cardiovasc µLar
0.01 0.01 USD
EPHA4 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cek 8 antibody; CEK8 antibody; EK8 antibody; eph receptor a4 antibody; EPH-like kinase 8 antibody; EPHA4 antibody; EPHA4_HUMAN antibody; Ephrin type-A receptor 4 antibody; HEK 8 antibody; hEK8 antibody; Receptor protein-tyrosine kinase HEK8 antibody; Sek 1 antibody; SEK antibody; TYRO 1 protein tyrosine kinase antibody; TYRO1 antibody; Tyrosine-protein kinase receptor SEK antibody; Tyrosine-protein kinase TYRO1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54764
Immunogen : Recombinant Human Ephrin type-A receptor 4 protein (345-545AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, mod µLates cell morphology and integrin-dependent cell adhesion thro µgh reg µLation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromusc µLar circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at \'Tyr-15\' which in turn phosphorylates NGEF reg µLating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vasc µLar formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling reg µLating for instance the development of the thymic epithelium.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPHA4
Research Areas : Neuroscience; Cardiovasc µLar; Signal transduction
0.01 0.01 USD
EPHA2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : ARCC2 antibody; AW545284 antibody; CTPA antibody; CTPP1 antibody; CTRCT6 antibody; EC 2.7.10.1 antibody; Eck antibody; Eph receptor A2 antibody; EPHA2 antibody; EPHA2_HUMAN antibody; Ephrin receptor antibody; Ephrin receptor EphA2 antibody; Ephrin type A receptor 2 antibody; Ephrin type-A receptor 2 antibody; Epithelial cell kinase antibody; Epithelial cell receptor protein tyrosine kinase antibody; Myk 2 antibody; Myk2 antibody; Sek 2 antibody; Sek2 antibody; Soluble EPHA2 variant 1 antibody; Tyrosine protein kinase receptor ECK antibody; Tyrosine-protein kinase receptor ECK antibody; Tyrosine-protein kinase receptor MPK-5 antibody; Tyrosine-protein kinase receptor SEK-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P29317
Immunogen : Recombinant Human Ephrin type-A receptor 2 protein (627-976AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 reg µLates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Reg µLates cell adhesion and differentiation thro µgh DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1 respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stim µLatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may reg µLate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling thro µgh reg µLation of osteoclastogenesis and osteoblastogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPHA2
Research Areas : Neuroscience; Cardiovasc µLar
0.01 0.01 USD
EPHA10 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : Ephrin type-A receptor 10 (EC 2.7.10.1), EPHA10
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5JZY3
Immunogen : Recombinant Human Ephrin type-A receptor 10 protein (242-564aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPHA10
Research Areas : Signal Transduction
0.01 0.01 USD
EPHA1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : EPH antibody; EPH receptor A1 antibody; EPH tyrosine kinase 1 antibody; EPH tyrosine kinase antibody; Epha1 antibody; EPHA1_HUMAN antibody; Ephrin receptor Eph A1 antibody; Ephrin type A receptor 1 antibody; Ephrin type-A receptor 1 antibody; EPHT 1 antibody; EPHT antibody; EPHT1 antibody; Erythropoietin producing hepatoma amplified sequence antibody; Erythropoietin-producing hepatoma receptor antibody; Esk antibody; hEpha1 antibody; MGC163163 antibody; Oncogene EPH antibody; Soluble EPHA1 variant 1 antibody; Soluble EPHA1 variant 2 antibody; Tyrosine protein kinase receptor EPH antibody; Tyrosine-protein kinase receptor EPH antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P21709
Immunogen : Recombinant Human Ephrin type-A receptor 1 protein (296-414AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracell µLar matrix inhibiting cell spreading and motility thro µgh reg µLation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and reg µLates cell proliferation. May play a role in apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPHA1
Research Areas : Neuroscience; Cardiovasc µLar; Signal transduction
0.01 0.01 USD
EPCAM Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 17 1A antibody; 323/A3 antibody; Adenocarcinoma associated antigen antibody; Adenocarcinoma-associated antigen antibody; Antigen identified by monoclonal antibody AUA1 antibody; AUA1 antibody; CD326 antibody; CD326 antigen antibody; Cell surface glycoprotein Trop 1 antibody; Cell surface glycoprotein Trop 2 antibody; Cell surface glycoprotein Trop-1 antibody; CO 17A antibody; CO17 1A antibody; CO17A antibody; DIAR5 antibody; EGP 2 antibody; EGP antibody; EGP2 antibody; EGP314 antibody; EGP40 antibody; Ep CAM antibody; Ep-CAM antibody; EPCAM antibody; EPCAM_HUMAN antibody; EpCAM1 antibody; Epithelial cell adhesion molec µLe antibody; Epithelial Cell Adhesion Molec µLe Intracell µLar Domain (EpCAM-ICD) antibody; Epithelial cell surface antigen antibody; Epithelial cell µLar adhesion molec µLe antibody; Epithelial glycoprotein 1 antibody; Epithelial glycoprotein 314 antibody; Epithelial glycoprotein antibody; ESA antibody; GA733 1 antibody; GA733 2 antibody; GA733-2 antibody; gastrointestinal tumor-associated antigen 2; 35-KD glycoprotein antibody; gp4 antibody; hEGP 2 antibody; hEGP314 antibody; HNPCC8 antibody; Human epithelial glycoprotein 2 antibody; KS 1/4 antigen antibody; KS1/4 antibody; KSA antibody; Ly74 antibody; Lymphocyte antigen 74 antibody; M1S 1 antibody; M1S2 antibody; M4S1 antibody; Major gastrointestinal tumor associated protein GA733 2 antibody; Major gastrointestinal tumor-associated protein GA733-2 antibody; mEGP314 antibody; Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody; Membrane component; chromosome 4; surface marker 1 antibody; Membrane component; chromosome 4; surface marker antibody; MIC18 antibody; MK 1 antibody; Protein 289A antibody; TACD1 antibody; TACSTD1 antibody; TROP1 antibody; Tumor associated calcium signal transducer 1 antibody; Tumor associated calcium signal transducer 2 precursor antibody; Tumor-associated calcium signal transducer 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16422
Immunogen : Recombinant Human Epithelial cell adhesion molec µLe protein (24-265AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May act as a physical homophilic interaction molec µLe between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-reg µLates the expression of FABP5, MYC and cyclins A and E.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPCAM
Research Areas : Tags & Cell Markers
0.01 0.01 USD
EPB2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : EPB2 antibody; Cysteine proteinase EP-B 2 antibody; EC 3.4.22.- antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Hordeum v µLgare (Barley)
UniProt ID : P25250
Immunogen : Recombinant Hordeum v µLgare Cysteine proteinase EP-B 2 protein (134-373AA)
Raised in : Rabbit
Species Reactivity : Hordeum v µLgare
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPB2
Research Areas : Others
0.01 0.01 USD
EPAS1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Basic helix loop helix PAS protein MOP2 antibody; Basic-helix-loop-helix-PAS protein MOP2 antibody; bHLHe73 antibody; Class E basic helix-loop-helix protein 73 antibody; ECYT4 antibody; Endothelial PAS domain containing protein 1 antibody; Endothelial pas domain protein 1 antibody; Endothelial PAS domain-containing protein 1 antibody; EPAS 1 antibody; EPAS-1 antibody; EPAS1 antibody; EPAS1_HUMAN antibody; HIF 1 alpha like factor antibody; HIF 2 alpha antibody; HIF-1-alpha-like factor antibody; HIF-2-alpha antibody; HIF2-alpha antibody; HIF2A antibody; HLF antibody; Hypoxia inducible factor 2 alpha antibody; Hypoxia inducible factor 2 alpha subunit antibody; Hypoxia-inducible factor 2-alpha antibody; Member of PAS protein 2 antibody; Member of pas superfamily 2 antibody; MOP 2 antibody; MOP2 antibody; PAS domain-containing protein 2 antibody; PASD2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99814
Immunogen : Recombinant Human Endothelial PAS domain-containing protein 1 protein (543-870AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor involved in the induction of oxygen reg µLated genes. Binds to core DNA sequence 5\'-[AG]CGTG-3\' within the hypoxia response element (HRE) of target gene promoters. Reg µLates the vasc µLar endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tub µLar system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox reg µLatory protein APEX seems to activate CTAD.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EPAS1
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cardiovasc µLar; Metabolism
0.01 0.01 USD
EP300 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : E1A associated protein p300 antibody; E1A binding protein p300 antibody; E1A-associated protein p300 antibody; EP300 antibody; EP300 : E1A binding protein p300 antibody; EP300_HUMAN antibody; Histone acetyltransferase p300 antibody; KAT3B antibody; p300 HAT antibody; RSTS2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q09472
Immunogen : Recombinant Human Histone acetyltransferase p300 protein (2283-2414AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions as histone acetyltransferase and reg µLates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene reg µLation by binding specifically to phosphorylated CREB protein. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stim µLates transcription, possibly by promoting nucleosome instability. Mediates acetylation of histone H3 at 'Lys-27' (H3K27ac). Also functions as acetyltransferase for nonhistone targets. Acetylates 'Lys-131' of ALX1 and acts as its coactivator. Acetylates SIRT2 and is proposed to indirectly increase the transcriptional activity of TP53 thro µgh acetylation and subsequent attenuation of SIRT2 deacetylase function. Acetylates HDAC1 leading to its inactivation and mod µLation of transcription. Acts as a TFAP2A-mediated transcriptional coactivator in presence of CITED2. Plays a role as a coactivator of NEUROD1-dependent transcription of the secretin and p21 genes and controls terminal differentiation of cells in the intestinal epithelium. Promotes cardiac myocyte enlargement. Can also mediate transcriptional repression. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. In case of HIV-1 infection, it is recruited by the viral protein Tat. Reg µLates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Acetylates FOXO1 and enhances its transcriptional activity. Acetylates BCL6 wich disrupts its ability to recruit histone deacetylases and hinders its transcriptional repressor activity. Participates in CLOCK or NPAS2-reg µLated rhythmic gene transcription; exhibits a circadian association with CLOCK or NPAS2, correlating with increase in PER1/2 mRNA and histone H3 acetylation on the PER1/2 promoter. Acetylates MTA1 at 'Lys-626' which is essential for its transcriptional coactivator activity (PubMed : 10733570, PubMed : 11430825, PubMed : 11701890, PubMed : 12402037, PubMed : 12586840, PubMed : 12929931 PubMed : 14645221 PubMed : 15186775, PubMed : 15890677, PubMed : 16617102, PubMed : 16762839, PubMed : 18722353, PubMed : 18995842, PubMed : 23415232, PubMed : 23911289, PubMed : 23934153, PubMed : 8945521). Acetylates XBP1 isoform 2; acetylation increases protein stability of XBP1 isoform 2 and enhances its transcriptional activity (PubMed : 20955178). Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed : 24939902). Acetylates MEF2D.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EP300
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Metabolism; Stem cells
2,848.56 2848.56 USD
EOMES Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : eomes antibody; EOMES_HUMAN antibody; Eomesodermin antibody; Eomesodermin homolog antibody; t box brain 2 antibody; T-box brain protein 2 antibody; T-brain-2 antibody; Tbr 2 antibody; TBR-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95936
Immunogen : Recombinant Human Eomesodermin homolog protein (562-676AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastr µLation, reg µLating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response reg µLating the expression of lytic effector genes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EOMES
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Developmental biology; Signal transduction; Stem cells
0.01 0.01 USD
ENY2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 1810057B09Rik antibody; 6720481I12 antibody; DC6 antibody; e(y)2 antibody; Enhancer of yellow 2 transcription factor homolog antibody; eny2 antibody; ENY2_HUMAN antibody; Ey2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NPA8
Immunogen : Recombinant Human Transcription and mRNA export factor ENY2 protein (1-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription reg µLatory histone acetylation (HAT) complex SAGA is a m µLtiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ENY2
Research Areas : Epigenetics and Nuclear Signaling; Cell biology; Signal transduction
0.01 0.01 USD