FITC

Volume : 50 µg
Clone Number :
Aliases : Fatty acid receptor 2 antibody; FFA2R antibody; Ffar2 antibody; FFAR2_HUMAN antibody; free fatty acid activated receptor 2 antibody; Free fatty acid receptor 2 antibody; G protein coupled receptor 43 antibody; G protein-coupled receptor 43 antibody; G-protein coupled receptor 43 antibody; GPR 43 antibody; GPR43 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15552
Immunogen : Recombinant Human Free fatty acid receptor 2 protein (277-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the reg µLation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molec µLes. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed : 12496283, PubMed : 12711604, PubMed : 23589301). Its activation res µLts in the formation of inositol 14,5-trisphosphate, the mobilization of intracell µLar calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracell µLar cAMP accum µLation. May play a role in glucose homeostasis by reg µLating the secretion of GLP-1 in response to short-chain fatty acids accum µLating in the intestine. May also reg µLate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also reg µLate whole-body energy homeostasis thro µgh adipogenesis reg µLating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, reg µLating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracell µLar lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed : 21037097). Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably acetate, propionate and butyrate (PubMed : 12496283, PubMed : 12711604). Exhibits a SCFA-independent constitutive G protein-coupled receptor activity (PubMed : 23066016).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FFAR2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FFA1R antibody; FFAR 1 antibody; Ffar1 antibody; FFAR1_HUMAN antibody; Free fatty acid receptor 1 antibody; G protein coupled receptor 40 antibody; G-protein coupled receptor 40 antibody; GPCR40 antibody; GPR 40 antibody; GPR40 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14842
Immunogen : Recombinant Human Free fatty acid receptor 1 protein (143-178AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stim µLated ins µLin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracell µLar calcium concentration. Seems to act thro µgh a G(q) and G(i)-mediated pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FFAR1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FEZ antibody; FEZ family zinc finger 1 antibody; Fez family zinc finger protein 1 antibody; fez like antibody; fezf1 antibody; FEZF1_HUMAN antibody; Zinc finger protein 312 like antibody; Zinc finger protein 312B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A0PJY2
Immunogen : Recombinant Human Fez family zinc finger protein 1 protein (1-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously reg µLate OSN axon projections. Reg µLates non-cell-autonomously the layer formation of the olfactory b µLb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FEZF1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Developmental biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : FEZ1Fascic µLation and elongation protein zeta-1 antibody; Zygin I antibody; Zygin-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99689
Immunogen : Recombinant Human Fascic µLation and elongation protein zeta-1 protein (12-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May be involved in axonal outgrowth as component of the network of molec µLes that reg µLate cell µLar morphology and axon guidance machinery. Able to restore partial locomotion and axonal fascic µLation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtub µLes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FEZ1
Research Areas : Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : ETS-domain transcription factor antibody; FEV (ETS oncogene family) antibody; FEV antibody; FEV ETS transcription factor antibody; FEV_HUMAN antibody; Fifth Ewing sarcoma variant antibody; Fifth Ewing variant protein antibody; HSRNAFEV antibody; mPet1 antibody; PC12 ETS domain-containing transcription factor 1 antibody; PC12 ETS factor 1 antibody; Pet-1 antibody; Protein FEV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99581
Immunogen : Recombinant Human Protein FEV protein (1-97AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions as a transcriptional reg µLator. According to PubMed : 12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FEV
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : Ferritin-2 antibody; chloroplastic antibody; EC 1.16.3.1 antibody; SFerH-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Glycine max (Soybean) (Glycine hispida)
UniProt ID : Q94IC4
Immunogen : Recombinant Glycine max Ferritin-2, chloroplastic protein (52-257AA)
Raised in : Rabbit
Species Reactivity : Glycine max
Tested Applications :
Background : Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Fermitin family homolog 3 antibody; Fermitin family member 3 antibody; FERMT3 antibody; Kind3 antibody; Kindlin 3 antibody; Kindlin-3 antibody; Kindlin3 antibody; MGC10966 antibody; MIG 2 antibody; MIG2 like protein antibody; MIG2-like protein antibody; MIG2B antibody; Unc 112 related protein 2 antibody; Unc-112-related protein 2 antibody; UNC112C antibody; URP2 antibody; URP2_HUMAN antibody; URP2SF antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86UX7
Immunogen : Recombinant Human Fermitin family homolog 3 protein (388-503AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a central role in cell adhesion in hematopoietic cells (PubMed : 19234463, PubMed : 26359933). Acts by activating the integrin beta-1-3 (ITGB1 ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed : 19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear gran µLocytes (PMNs) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FERMT3
Research Areas : Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ34213 antibody; FLJ44462 antibody; UNC112 antibody; FERM2_HUMAN antibody; Fermitin family homolog 2 antibody; Fermt2 antibody; KIND2 antibody; Kindlin-2 antibody; MIG-2 antibody; MIG2 antibody; Mitogen-inducible gene 2 protein antibody; PH domain-containing family C member 1 antibody; Pleckstrin homology domain containing family C (with FERM domain) member 1 antibody; Pleckstrin homology domain-containing family C member 1 antibody; PLEKHC1 antibody; UNC112B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96AC1
Immunogen : Recombinant Human Fermitin family homolog 2 protein (155-232AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracell µLar matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracell µLar matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape mod µLation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the reg µLation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FERMT2
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : C20orf42 antibody; Chromosome 20 open reading frame 42 antibody; DTGCU 2 antibody; DTGCU2 antibody; FERM1_HUMAN antibody; Fermitin family homolog 1 antibody; Fermitin family member 1 antibody; Fermt1 antibody; FLJ20116 antibody; FLJ23423 antibody; KIND 1 antibody; KIND1 antibody; Kinderlin antibody; Kindlerin antibody; Kindlin 1 antibody; Kindlin syndrome protein antibody; Kindlin-1 antibody; Kindlin1 antibody; Unc 112 related protein 1 antibody; Unc-112-related protein 1 antibody; Unc112 related protein antibody; UNC112A antibody; URP 1 antibody; URP1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BQL6
Immunogen : Recombinant Human Fermitin family homolog 1 protein (321-420AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FERMT1
Research Areas : Tags & Cell Markers

Volume : 50 µg
Clone Number :
Aliases : Basic helix-loop-helix protein N-twist antibody; bHLHa31 antibody; Class A basic helix-loop-helix protein 31 antibody; Fer3 like (Drosophila) antibody; Fer3-like protein antibody; FER3L_HUMAN antibody; Ferd3l antibody; MGC119861 antibody; N TWIST antibody; NATO3 antibody; Nephew of atonal 3 antibody; Neuronal twist antibody; NTWIST antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96RJ6
Immunogen : Recombinant Human Fer3-like protein (1-167AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FERD3L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : FEN1 antibody; At5g26680 antibody; F21E10.3Flap endonuclease 1 antibody; FEN-1 antibody; EC 3.1.-.- antibody; Flap structure-specific endonuclease 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Arabidopsis thaliana (Mus musc µLus (Mouse)-ear cress)
UniProt ID : O65251
Immunogen : Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)
Raised in : Rabbit
Species Reactivity : Arabidopsis thaliana
Tested Applications :
Background : Structure-specific nuclease with 5\'-flap endonuclease and 5\'-3\' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5\'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. It enters the flap from the 5\'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinicapyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5\'-3\' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FEN1
Research Areas : Epigenetics and Nuclear Signaling