FITC

Volume : 50 µg
Clone Number :
Aliases : FBXW5 antibody; FBW5 antibody; PP3971F-box/WD repeat-containing protein 5 antibody; F-box and WD-40 domain-containing protein 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q969U6
Immunogen : Recombinant Human F-box/WD repeat-containing protein 5 protein (265-494AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate recognition component of both SCF (SKP1-C µL1-F-box protein) and DCX (DDB1-C µL4-X-box) E3 ubiquitin-protein ligase complexes. Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication. The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-reg µLator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression. Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2. May also act as a negative reg µLator of MAP3K7/TAK1 signaling in the interleukin-1B (IL1B) signaling pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXW5
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : F box and WD 40 domain containing protein 2 antibody; F box and WD repeat domain containing 2 antibody; F box and WD40 domain protein 2 antibody; F box/WD repeat containing protein 2 antibody; F-box and WD-40 domain-containing protein 2 antibody; F-box/WD repeat-containing protein 2 antibody; FBW 2 antibody; FBW2 antibody; FBXW 2 antibody; Fbxw2 antibody; FBXW2_HUMAN antibody; Fwd2 antibody; Md6 antibody; Protein MD6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKT8
Immunogen : Recombinant Human F-box/WD repeat-containing protein 2 protein (72-340AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXW2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : FBXW12 antibody; FBW12 antibody; FBXO12 antibody; FBXO35F-box/WD repeat-containing protein 12 antibody; F-box and WD-40 domain-containing protein 12 antibody; F-box only protein 35 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6X9E4
Immunogen : Recombinant Human F-box/WD repeat-containing protein 12 protein (1-250AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXW12
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Fbxw10F-box/WD repeat-containing protein 10 antibody; F-box and WD-40 domain-containing protein 10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : Q5SUS0
Immunogen : Recombinant Mouse F-box/WD repeat-containing protein 10 protein (701-1030AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Probable substrate-recognition component of a SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Fbxw10
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Cross-immune reaction antigen 1 antibody; dJ341E18.2 antibody; DKFZp434C0118 antibody; F-box only protein 9 antibody; Fbp24 antibody; FBX09 antibody; FBX9 antibody; FBX9_HUMAN antibody; Fbxo9 antibody; KIAA0936 antibody; NY REN 57 antibody; OTTHUMP00000016628 antibody; OTTHUMP00000016629 antibody; OTTHUMP00000214588 antibody; Renal carcinoma antigen NY-REN-57 antibody; VCIA1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UK97
Immunogen : Recombinant Human F-box only protein 9 protein (13-111AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate recognition component of a SCF (SKP1-C µL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly reg µLating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO9
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : 5730411K09 antibody; AV001623 antibody; DKFZp781J0852 antibody; F box gene 3 antibody; F box only protein 44 antibody; F box only protein 6a antibody; F box protein 44 antibody; F box protein FBX30 antibody; F box/G domain protein 3 antibody; F-box only protein 44 antibody; F-box protein FBX30 antibody; F-box/G-domain protein 3 antibody; FBG3 antibody; FBX30 antibody; FBX44 antibody; FBX44_HUMAN antibody; FBX6A antibody; Fbxo44 antibody; Fbxo6a antibody; MGC14140 antibody; RGD1562463 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H4M3
Immunogen : Recombinant Human F-box only protein 44 protein (1-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO44
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : F box only protein 40 antibody; F box protein 40 antibody; F-box only protein 40 antibody; FBX40 antibody; FBX40_HUMAN antibody; Fbxo40 antibody; KIAA1195 antibody; Muscle disease related protein antibody; Muscle disease-related protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UH90
Immunogen : Recombinant Human F-box only protein 40 protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable substrate-recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO40
Research Areas : Cell biology

Volume : 50 µL
Clone Number :
Aliases : FBXO36 antibody; FBX36F-box only protein 36 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NEA4
Immunogen : Recombinant Human F-box only protein 36 protein (1-188AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO36
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : FBXO30 antibody; FBX30F-box only protein 30 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TB52
Immunogen : Recombinant Human F-box only protein 30 protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO30
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : F Box G - Domain 3 antibody; F box only protein 3 antibody; F box protein 3 antibody; F box protein FBX3 antibody; F-box only protein 3 antibody; FBA antibody; FBX3 antibody; FBX3_HUMAN antibody; FBXO3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UK99
Immunogen : Recombinant Human F-box only protein 3 protein (276-376AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate recognition component of the SCF (SKP1-C µL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CENP 30 antibody; Centromere protein 30 antibody; F box only protein 28 antibody; F box protein 28 antibody; F-box only protein 28 antibody; Fbx28 antibody; FBX28_HUMAN antibody; FBXO28 antibody; FLJ10766 antibody; KIAA0483 antibody; OTTHUMP00000035597 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NVF7
Immunogen : Recombinant Human F-box only protein 28 protein (251-368AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FBXO28
Research Areas : Cell biology