FITC

Volume : 50 µg
Clone Number :
Aliases : A16L1_HUMAN antibody; APG16 like 1 antibody; APG16-like 1 antibody; APG16L antibody; APG16L beta antibody; ATG16 autophagy related 16 like 1 antibody; ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody; ATG16A antibody; ATG16L antibody; Atg16l1 antibody; Autophagy related protein 16 1 antibody; Autophagy-related protein 16-1 antibody; FLJ00045 antibody; FLJ10035 antibody; FLJ10828 antibody; FLJ22677 antibody; IBD10 antibody; OTTHUMP00000164391 antibody; OTTHUMP00000164393 antibody; OTTHUMP00000165876 antibody; OTTHUMP00000165877 antibody; WD repeat domain 30 antibody; WDR30 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q676U5
Immunogen : Recombinant Human Autophagy-related protein 16-1 protein (1-607AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays an essential role in autophagy : interacts with ATG12-ATG5 to mediate the conj µgation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG16L1
Research Areas : Neuroscience; Cancer; Cardiovasc µLar; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 4832427M01 antibody; ATG14 antibody; Atg14L antibody; Autophagy-related protein 14-like protein antibody; BAKOR_HUMAN antibody; Barkor antibody; Beclin 1-associated autophagy-related key reg µLator antibody; D14Ertd114e antibody; D14Ertd436e antibody; KIAA0831 antibody; mCG_6911 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6ZNE5
Immunogen : Recombinant Human Beclin 1-associated autophagy-related key reg µLator protein (1-492AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed : 18843052, PubMed : 19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conj µgation to phosphatidylethanolamine (PubMed : 19270696, PubMed : 20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed : 20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed : 23878393). Stim µLates the phosphorylation of BECN1 but suppresses the phosphorylation PIK3C3 by AMPK (PubMed : 23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed : 25686604). Mod µLates the hepatic lipid metabolism (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG14
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ATG13 antibody; ATG13 autophagy related 13 homolog (S. cerevisiae) antibody; ATG13_HUMAN antibody; Autophagy related 13 antibody; Autophagy related protein 13 antibody; Autophagy-related protein 13 antibody; FLJ20698 antibody; KIAA0652 antibody; OTTHUMP00000233321 antibody; OTTHUMP00000233322 antibody; OTTHUMP00000233323 antibody; OTTHUMP00000233324 antibody; OTTHUMP00000233325 antibody; OTTHUMP00000233326 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75143
Immunogen : Recombinant Human Autophagy-related protein 13 protein (315-517AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that reg µLates autophagy thro µgh the control of the phosphorylation status of ATG13 and µLK1 and the reg µLation of the ATG13- µLK1-RB1CC1 complex. Thro µgh its reg µLation of µLK1 activity, plays a role in the reg µLation of the kinase activity of mTORC1 and cell proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG13
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : ATG101 antibody; Atg13-interacting protein antibody; ATGA1_HUMAN antibody; Autophagy-related protein 101 antibody; C12orf44 antibody; Chromosome 12 open reading frame 44 antibody; FLJ11773 antibody; OTTHUMP00000241687 antibody; OTTHUMP00000241688 antibody; OTTHUMP00000241689 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BSB4
Immunogen : Recombinant Human Autophagy-related protein 101 protein (1-218AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG101
Research Areas : Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : Apg 10 antibody; APG 10L antibody; APG10 antibody; APG10 autophagy 10 like antibody; APG10 like antibody; APG10; S. cerevisiae; homolog of antibody; APG10-like antibody; APG10L antibody; ATG 10 antibody; ATG10 antibody; ATG10 autophagy related 10 homolog (S. cerevisiae) antibody; ATG10 autophagy related 10 homolog antibody; ATG10_HUMAN antibody; autophagy 10; S. cerevisiae; homolog of antibody; Autophagy related protein 10 antibody; Autophagy-related protein 10 antibody; DKFZP586I0418 antibody; FLJ13954 antibody; pp12616 antibody; Ubiquitin-like-conj µgating enzyme ATG10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H0Y0
Immunogen : Recombinant Human Ubiquitin-like-conj µgating enzyme ATG10 protein (1-50AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conj µgation of ATG12 to ATG5. ATG12 conj µgation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molec µLe. Not involved in ATG12 conj µgation to ATG3. Plays a role in adenovirus-mediated cell lysis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG10
Research Areas : Neuroscience; Cancer; Cardiovasc µLar; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : ATG1 antibody; CAGL0L06006g antibody; Serine/threonine-protein kinase ATG1 antibody; EC 2.7.11.1 antibody; Autophagy-related protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Candida glabrata
UniProt ID : Q6FL58
Immunogen : Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA)
Raised in : Rabbit
Species Reactivity : Candida glabrata
Tested Applications :
Background : Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to reg µLate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to f µLfill cell µLar energy requirements and preventing excess ROS production. Also involved in endoplasmic retic µLum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling thro µgh the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 thro µgh phosphorylation of ATG9.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG1
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : Activating transcription factor 6 alpha antibody; Activating transcription factor 6 antibody; ATF 6 antibody; ATF6 alpha antibody; ATF6 antibody; ATF6-alpha antibody; ATF6A antibody; ATF6A_HUMAN antibody; cAMP dependent transcription factor ATF 6 alpha antibody; cAMP-dependent transcription factor ATF-6 alpha antibody; Cyclic AMP dependent transcription factor ATF 6 alpha antibody; DKFZp686P2194 antibody; ESTM49 antibody; FLJ21663 antibody; Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody; Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18850
Immunogen : Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha protein (1-194AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transmembrane glycoprotein of the endoplasmic retic µLum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic retic µLum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5\'-CCAC[GA]-3\'half of the ER stress response element (ERSE) (5\'-CCAAT-N(9)-CCAC[GA]-3\') and of ERSE II (5\'-ATTGG-N-CCACG-3\'). Binding to ERSE requires binding of NF-Y to ERSE. Co µLd also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATF6
Research Areas : Signal Transduction

Volume : 50 µL
Clone Number :
Aliases : ATF5 antibody; ATFXCyclic AMP-dependent transcription factor ATF-5 antibody; cAMP-dependent transcription factor ATF-5 antibody; Activating transcription factor 5 antibody; Transcription factor ATFx antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2D1
Immunogen : Recombinant Human Cyclic AMP-dependent transcription factor ATF-5 protein (1-282AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor that either stim µLates or represses gene transcription thro µgh binding of different DNA reg µLatory elements such as cAMP response element (CRE) (consensus : 5\'-GTGACGT[AC][AG]-3\'), ATF5-specific response element (ARE) (consensus : 5\'-C[CT]TCT[CT]CCTT[AT]-3\') but also the amino acid response element (AARE), present in many viral and cell µLar promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation (PubMed : 10373550, PubMed : 15358120, PubMed : 21212266, PubMed : 20654631). Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4 (PubMed : 15358120). Important reg µLator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-reg µLated in order for such cells to exit the cycle and differentiate (By similarity). Participates in the pathways by which SHH promotes cerebellar gran µLe neuron progenitor cells proliferation (By similarity). Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes (By similarity). May be involved in osteogenic differentiation (PubMed : 22442021). Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1. Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1 (PubMed : 21791614). Plays an anti-apoptotic role thro µgh the transcriptional reg µLation of BCL2, this function seems to be cell type-dependent (By similarity). Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver (PubMed : 18332083). In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase (PubMed : 22528486, PubMed : 18701499). May act as a negative reg µLator of IL1B transduction pathway in liver (PubMed : 24379400). Upon IL1B stim µLus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members (PubMed : 25512613). Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation (PubMed : 24216764). Reg µLates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner. Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material (PubMed : 26213385).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATF5
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : Activating transcription factor 4 antibody; ATF 4 antibody; ATF4 antibody; ATF4 protein antibody; ATF4_HUMAN antibody; cAMP-dependent transcription factor ATF-4 antibody; cAMP-responsive element-binding protein 2 antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; Cyclic AMP dependent transcription factor ATF 4 antibody; Cyclic AMP response element binding protein 2 antibody; Cyclic AMP-dependent transcription factor ATF-4 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; DNA binding protein TAXREB67 antibody; DNA-binding protein TAXREB67 antibody; Tax Responsive Enhancer Element B67 antibody; Tax-responsive enhancer element-binding protein 67 antibody; TaxREB67 antibody; TXREB antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18848
Immunogen : Recombinant Human Cyclic AMP-dependent transcription factor ATF-4 protein (20-200aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptional activator. Binds the cAMP response element (CRE) (consensus : 5\'-GTGACGT[AC][AG]-3\'), a sequence present in many viral and cell µLar promoters. Cooperates with FOXO1 in osteoblasts to reg µLate glucose homeostasis thro µgh suppression of beta-cell production and decrease in ins µLin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Reg µLates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic retic µLum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by reg µLating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Reg µLates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes. During ER stress response, activates the transcription of NLRP1 possibly in concert with other factors (PubMed : 26086088).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATF4
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : Activating transcription factor 3 antibody; ATF3 antibody; ATF3_HUMAN antibody; ATF3deltaZip2 antibody; ATF3deltaZip2c antibody; ATF3deltaZip3 antibody; cAMP dependent transcription factor ATF3 antibody; cAMP-dependent transcription factor ATF-3 antibody; Cyclic AMP dependent transcription factor ATF3 antibody; Cyclic AMP-dependent transcription factor ATF-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18847
Immunogen : Recombinant Human Cyclic AMP-dependent transcription factor ATF-3 protein (1-181AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : This protein binds the cAMP response element (CRE) (consensus : 5\\\'-GTGACGT[AC][AG]-3\\\'), a sequence present in many viral and cell µLar promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATF3
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : AI225793 antibody; Arginine tRNA protein transferase 1 antibody; Arginine-tRNA--protein transferase 1 antibody; Arginyl-tRNA--protein transferase 1 antibody; Arginyl-tRNA-protein transferase antibody; Arginyltransferase 1 antibody; Ate1 antibody; ATE1_HUMAN antibody; AW547406 antibody; EC 2.3.2.8 antibody; MGC26724 antibody; OTTHUMP00000020637 antibody; OTTHUMP00000058665 antibody; R transferase 1 antibody; R-transferase 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95260
Immunogen : Recombinant Human Arginyl-tRNA--protein transferase 1 protein (105-253AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the post-translational conj µgation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATE1
Research Areas : Cell biology