FITC

Volume : 50 µg
Clone Number :
Aliases : IMDH2_HUMAN antibody; IMP (inosine monophosphate) dehydrogenase 2 antibody; IMP dehydrogenase 2 antibody; IMP oxireductase 2 antibody; IMPD 2 antibody; IMPD2 antibody; IMPDH 2 antibody; IMPDH II antibody; IMPDH-II antibody; Impdh2 antibody; Inosine 5' monophosphate dehydrogenase 2 antibody; Inosine 5' phosphate dehydrogenase 2 antibody; Inosine monophosphate dehydrogenase type II antibody; Inosine-5''-monophosphate dehydrogenase 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P12268
Immunogen : Recombinant Human Inosine-5\'-monophosphate dehydrogenase 2 protein (5-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the conversion of inosine 5\'-phosphate (IMP) to xanthosine 5\'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the reg µLation of cell growth. Co µLd also have a single-stranded nucleic acid-binding activity and co µLd play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IMPDH2
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : IMDH1_HUMAN antibody; IMP (inosine monophosphate) dehydrogenase 1 antibody; IMP dehydrogenase 1 antibody; IMPD 1 antibody; IMPD antibody; IMPD1 antibody; IMPDH 1 antibody; IMPDH I antibody; IMPDH-I antibody; Impdh1 antibody; Inosine 5' monophosphate dehydrogenase 1 antibody; Inosine monophosphate dehydrogenase 1 antibody; Inosine-5''-monophosphate dehydrogenase 1 antibody; LCA11 antibody; RP10 antibody; sWSS2608 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20839
Immunogen : Recombinant Human Inosine-5\'-monophosphate dehydrogenase 1 protein (191-281AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the conversion of inosine 5\'-phosphate (IMP) to xanthosine 5\'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the reg µLation of cell growth. Co µLd also have a single-stranded nucleic acid-binding activity and co µLd play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IMPDH1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : IMPACT antibody; Impact homolog (mouse) antibody; Impact homolog antibody; impact RWD domain protein antibody; IMPCT_HUMAN antibody; Imprinted and ancient gene protein homolog antibody; MGC33718 antibody; Protein IMPACT antibody; RWD domain containing 5 antibody; RWDD5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2X3
Immunogen : Recombinant Human Protein IMPACT protein (41-320AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Translational reg µLator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1 thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-reg µLation of protein synthesis. May be required to reg µLate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Thro µgh its action on GCN2, may also facilitate neuritogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IMPACT
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Cell proliferation inducing protein 52 antibody; Cell proliferation-inducing gene 4/52 protein antibody; Heart muscle protein antibody; HMP antibody; IMMT antibody; IMMT_HUMAN antibody; Inner membrane protein mitochondrial antibody; Inner mitochrondial membrane antibody; MICOS complex subunit MIC60 antibody; MINOS2 antibody; Mitochondrial inner membrane organizing system 2 antibody; Mitochondrial inner membrane protein antibody; Mitofilin antibody; Motor protein antibody; p87 antibody; p87/89 antibody; p89 antibody; pig4 antibody; PIG52 antibody; Proliferation-inducing gene 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16891
Immunogen : Recombinant Human MICOS complex subunit MIC60 protein (76-215AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed : 22114354, PubMed : 25781180).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IMMT
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 209L8 antibody; Acetolactate synthase homolog antibody; Acetolactate synthase like protein antibody; acetolactate synthase, bacterial, homolog of antibody; Acetolactate synthase-like protein antibody; AHAS antibody; FLJ39061 antibody; ILV2H antibody; IlvB (bacterial acetolactate synthase) like antibody; IlvB like protein antibody; IlvB-like protein antibody; Ilvbl antibody; ILVBL_HUMAN antibody; MGC1269 antibody; MGC19535 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A1L0T0
Immunogen : Recombinant Human Acetolactate synthase-like protein (45-344AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : membrane
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ILVBL
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DKFZp434J2031 antibody; FLJ10181 antibody; ILKAP antibody; ILKAP_HUMAN antibody; ILKAP2 antibody; ILKAP3 antibody; Integrin linked kinase associated phosphatase antibody; Integrin linked kinase associated serine/threonine phosphatase 2C antibody; Integrin linked kinase associated serine/threonine phosphatase antibody; Integrin-linked kinase-associated serine/threonine phosphatase 2C antibody; MGC4846 antibody; PP2C DELTA antibody; Protein phosphatase 2c delta isozyme antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H0C8
Immunogen : Recombinant Human Integrin-linked kinase-associated serine/threonine phosphatase 2C protein (1-392AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Protein phosphatase that may play a role in reg µLation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to mod µLate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ILKAP
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dlk antibody; Dual leucine zipper bearing kinase antibody; Dual leucine zipper kinase DLK antibody; Leucine-zipper protein kinase antibody; M3K12_HUMAN antibody; Map3k12 antibody; MAPK-upstream kinase antibody; MEKK12 antibody; Mitogen-activated protein kinase kinase kinase 12 antibody; Mixed lineage kinase antibody; MUK antibody; Protein kinase MUK antibody; ZPK antibody; ZPKP1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q12852
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 12 protein (101-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K12
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 2610017K16Rik antibody; EC 2.7.11.25 antibody; M3K11_HUMAN antibody; Map3k11 antibody; MEKK11 antibody; MGC17114 antibody; Mitogen-activated protein kinase kinase kinase 11 antibody; Mixed lineage kinase 3 antibody; Mixed lineage protein kinase 3 antibody; Mlk-3 antibody; Mlk3 antibody; Protein tyrosine kinase PTK1 antibody; PTK1 antibody; RHOE antibody; SH3 domain containing proline rich kinase antibody; SPRK antibody; Src-homology 3 domain-containing proline-rich kinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16584
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 11 protein (536-693AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Activates the JUN N-terminal pathway. Required for serum-stim µLated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) thro µgh phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stim µLated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtub µLe organization during the cell cycle.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K11
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Map3k1 antibody; Mekk antibody; Mekk1 antibody; Mitogen-activated protein kinase kinase kinase 1 antibody; EC 2.7.11.25 antibody; MAPK/ERK kinase kinase 1 antibody; MEK kinase 1 antibody; MEKK 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P53349
Immunogen : Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Map3k1
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : c-Jun N-terminal kinase kinase 2 antibody; Dual specificity mitogen activated protein kinase kinase 7 antibody; Dual specificity mitogen-activated protein kinase kinase 7 antibody; JNK activating kinase 2 antibody; JNK kinase 2 antibody; JNK-activating kinase 2 antibody; JNKK 2 antibody; Jnkk-2 antibody; Jnkk2 antibody; MAP kinase kinase 7 antibody; MAP2K7 antibody; MAPK/ERK kinase 7 antibody; MAPKK 7 antibody; MAPKK-7 antibody; MAPKK7 antibody; MEK 7 antibody; Mitogen Activated Protein Kinase kinase 7 antibody; MKK 7 antibody; MKK-7 antibody; MKK7 antibody; MP2K7_HUMAN antibody; PRKMK 7 antibody; PRKMK-7 antibody; PRKMK7 antibody; SAPK kinase 4 antibody; SAPKK-4 antibody; SAPKK4 antibody; Sek 2 antibody; Sek-2 antibody; Sek2 antibody; SKK4 antibody; stress-activated protein kinase kinase 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14733
Immunogen : Recombinant Human Dual specificity mitogen-activated protein kinase kinase 7 protein (17-160AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1 MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP2K7
Research Areas : Immunology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dual specificity mitogen activated protein kinase kinase 6 antibody; Dual specificity mitogen-activated protein kinase kinase 6 antibody; MAP kinase kinase 6 antibody; MAP2K6 antibody; MAPK/ERK kinase 6 antibody; MAPKK 6 antibody; MAPKK6 antibody; MEK 6 antibody; MEK6 antibody; Mitogen Activated Protein Kinase Kinase 6 antibody; MKK 6 antibody; MKK6 antibody; MP2K6_HUMAN antibody; PRKMK6 antibody; protein kinase antibody; Protein kinase mitogen activated kinase 6 antibody; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) antibody; SAPK kinase 3 antibody; SAPKK-3 antibody; SAPKK3 antibody; SKK3 antibody; Stress-activated protein kinase kinase 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52564
Immunogen : Recombinant Human Dual specificity mitogen-activated protein kinase kinase 6 protein (1-334AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11 MAPK12, MAPK13 and MAPK14 and plays an important role in the reg µLation of cell µLar responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF. MAP2K6/MKK6 also phosphorylates and activates PAK6. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Nuclear targets of p38 MAP kinase include the transcription factors ATF2 and ELK1. Within the p38 MAPK signal transduction pathway, MAP3K6/MKK6 mediates phosphorylation of STAT4 thro µgh MAPK14 activation, and is therefore required for STAT4 activation and STAT4-reg µLated gene expression in response to IL-12 stim µLation. The pathway is also crucial for IL-6-induced SOCS3 expression and down-reg µLation of IL-6-mediated gene induction; and for IFNG-dependent gene transcription. Has a role in osteoclast differentiation thro µgh NF-kappa-B transactivation by TNFSF11 and in endochondral ossification and since SOX9 is another likely downstream target of the p38 MAPK pathway. MAP2K6/MKK6 mediates apoptotic cell death in thymocytes. Acts also as a reg µLator for melanocytes dendricity, thro µgh the mod µLation of Rho family GTPases.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP2K6
Research Areas : Cell biology; Immunology; Signal transduction