FITC

Volume : 50 µg
Clone Number :
Aliases : Aa2-050 antibody; AU019800 antibody; AU021329 antibody; AU043350 antibody; AW146323 antibody; BUB 3 antibody; BUB 3L antibody; BUB3 (budding uninhibited by benzimidazoles 3; yeast) homolog antibody; bub3 antibody; BUB3 budding uninhibited by benzimidazoles 3 homolog antibody; BUB3 mitotic checkpoint protein antibody; BUB3_HUMAN antibody; BUB3L antibody; Budding uninhibited by benomyl antibody; Budding uninhibited by benzimidazoles 3 antibody; Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) antibody; Budding uninhibited by benzimidazoles 3 homolog (yeast) antibody; Budding uninhibited by benzimidazoles 3 homolog antibody; Budding uninhibited by benzimidazoles 3; S. cerevisiae; homolog of antibody; C78067 antibody; hBUB3 antibody; Mitotic checkpoint component antibody; Mitotic checkpoint protein bub3 antibody; OTTHUMP00000020679 antibody; OTTHUMP00000020680 antibody; WD repeat type I transmembrane protein A72.5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43684
Immunogen : Recombinant Human Mitotic checkpoint protein BUB3 protein (6-217AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtub µLe (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Reg µLates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUB3
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Beta homolg of S. cerevisiae BUB 1 antibody; Beta homolg of S. cerevisiae budding uninhibited by benzimidazoles antibody; BUB 1B antibody; BUB1 budding uninhibited by benzimidazoles 1 homolog beta antibody; Bub1A antibody; BUB1B antibody; BUB1B_HUMAN antibody; BUB1beta antibody; BUBR1 antibody; Budding Uninhibited by Benzimidazoles 1 beta antibody; Budding uninhibited by benzimidazoles 1 homolog beta (yeast) antibody; hBUBR1 antibody; MAD3/BUB1 related protein kinase antibody; MAD3/BUB1-related protein kinase antibody; MAD3L antibody; Mitotic checkpoint gene BUB1B antibody; Mitotic checkpoint kinase MAD3L antibody; Mitotic checkpoint serine/threonine protein kinase BUB1 beta antibody; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody; MVA1 antibody; OTTHUMP00000160319 antibody; Protein SSK1 antibody; SSK 1 antibody; SSK1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60566
Immunogen : Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein (230-394AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively reg µLates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUB1B
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Bub1 antibody; BUB1 budding uninhibited by benzimidazoles 1 homolog antibody; BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) antibody; BUB1 mitotic checkpoint serine/threonine kinase antibody; BUB1; S. cerevisiae; homolog of antibody; BUB1_HUMAN antibody; BUB1A antibody; BUB1L antibody; Budding uninhibited by benzimidazoles 1 (yeast homolog) antibody; Budding uninhibited by benzimidazoles 1 homolog antibody; Budding uninhibited by benzimidazoles 1; S. cerevisiae; homolog of antibody; hBUB1 antibody; Homolog of mitotic checkpoint gene BUB1 antibody; Mitotic checkpoint gene BUB1 antibody; Mitotic checkpoint serine/threonine protein kinase BUB1 antibody; Mitotic checkpoint serine/threonine-protein kinase BUB1 antibody; Mitotic spindle checkpoint kinase antibody; Putative serine/threonine protein kinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43683
Immunogen : Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 protein (256-577AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase that performs 2 crucial functions during mitosis : it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1. Required for the kinetochore localization of PLK1. Plays an important role in defining SGO1 localization and thereby affects sister chromatid cohesion. Acts as a substrate for anaphase-promoting complex or cyclosome (APC/C) in complex with its activator CDH1 (APC/C-Cdh1). Necessary for ensuring proper chromosome segregation and binding to BUB3 is essential for this function. Can reg µLate chromosome segregation in a kinetochore-independent manner. Can phosphorylate BUB3. The BUB1-BUB3 complex plays a role in the inhibition of APC/C when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1. Kinase activity is essential for inhibition of APC/CCDC20 and for chromosome alignment but does not play a major role in the spindle-assembly checkpoint activity. Mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUB1
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Beta transducin repeat containing E3 ubiquitin protein ligase antibody; beta TrCP1 antibody; beta-transducin repeat containing antibody; BETA-TRCP antibody; betaTrCP antibody; btrC antibody; bTrCP antibody; bTrCP1 antibody; E3RSIkappaB antibody; F box and WD repeat protein 1B antibody; F box and WD repeats protein beta TrCP antibody; F-box and WD repeats protein beta-TrCP antibody; F-box/WD repeat protein 1A antibody; F-box/WD repeat-containing protein 1A antibody; FBW1A antibody; FBW1A_HUMAN antibody; FBXW1 antibody; FBXW1A antibody; FWD1 antibody; HOS antibody; mKIAA4123 antibody; pIkappaBalpha-E3 receptor subunit antibody; Slimb antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y297
Immunogen : Recombinant Human F-box/WD repeat-containing protein 1A protein (397-448AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate recognition component of a SCF (SKP1-C µL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins. SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. Ubiquitination of NFKBIA occurs at \'Lys-21\' and \'Lys-22\'. SCF(BTRC) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed : 25704143, PubMed : 25503564). SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1/nuclear factor NF-kappa-B p105 subunit, ATF4, CDC25A, DLG1 FBXO5, PER1 SMAD3, SMAD4, SNAI1 and probably NFKB2. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2. May be involved in ubiquitination and subsequent proteasomal degradation thro µgh a DBB1-C µL4 E3 ubiquitin-protein ligase. Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1 IKBKB and TNF. Required for proteolytic processing of GLI3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTRC
Research Areas : Neuroscience; Cell biology; Microbiology

Volume : 50 µg
Clone Number :
Aliases : BTNL9 antibody; UNQ1900/PRO4346Butyrophilin-like protein 9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6UXG8
Immunogen : Recombinant Human Butyrophilin-like protein 9 protein (35-256AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTNL9
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : BTNL3 antibody; BTNL3_HUMAN antibody; BTNLR antibody; Butyrophilin like protein 3 antibody; Butyrophilin like receptor antibody; Butyrophilin-like protein 3 antibody; Butyrophilin-like receptor antibody; COLF4100 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6UXE8
Immunogen : Recombinant Human Butyrophilin-like protein 3 protein (18-237AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTNL3
Research Areas : Immunology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BTNL2Butyrophilin-like protein 2 antibody; BTL-II antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UIR0
Immunogen : Recombinant Human Butyrophilin-like protein 2 protein (26-202AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Negative reg µLator of T-cell proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTNL2
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : BT3A3_HUMAN antibody; BTF3 antibody; BTN3A3 antibody; Butyrophilin subfamily 3 member A3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00478
Immunogen : Recombinant Human Butyrophilin subfamily 3 member A3 protein (30-248AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in T-cell responses in the adaptive immune response.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN3A3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BT3.2 antibody; BT3.3 antibody; BT3A2_HUMAN antibody; BTF4 antibody; BTN3A 2 antibody; BTN3A2 antibody; Butyrophilin protein antibody; Butyrophilin subfamily 3 member A2 antibody; Butyrophilin; subfamily 3; member A2 antibody; CD277 antibody; FLJ40011 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78410
Immunogen : Recombinant Human Butyrophilin subfamily 3 member A2 protein (30-248AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN3A2
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : BT3A1_HUMAN antibody; BTN3A1 antibody; Butyrophilin subfamily 3 member A1 antibody; CD277 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00481
Immunogen : Recombinant Human Butyrophilin subfamily 3 member A1 protein (30-254AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in T-cell activation and in the adaptive immune response. Reg µLates the proliferation of activated T-cells. Reg µLates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN3A1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BT2.2 antibody; BT2A2_HUMAN antibody; BTF2 antibody; BTN2A2 antibody; butyrophilin 2 antibody; Butyrophilin subfamily 2 member A2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WVV5
Immunogen : Recombinant Human Butyrophilin subfamily 2 member A2 protein (33-262AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN2A2
Research Areas : Cancer; Cell biology; Immunology