Volume : 50 µg
Clone Number :
Aliases : 18 kDa phosphoprotein antibody; CFL 1 antibody; CFL antibody; CFL1 antibody; COF1_HUMAN antibody; Cofilin 1 antibody; Cofilin 1 non muscle antibody; Cofilin antibody; Cofilin non muscle isoform antibody; Cofilin-1 antibody; epididymis secretory protein Li 15 antibody; HEL-S-15 antibody; non-muscle isoform antibody; p18 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P23528
Immunogen : Recombinant Human Cofilin-1 protein (4-144AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Reg µLates actin cytoskeleton dynamics. Important for normal progress thro µgh mitosis and normal cytokinesis. Plays a role in the reg µLation of cell morphology and cytoskeletal organization. Required for the up-reg µLation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed : 11812157, PubMed : 15580268, PubMed : 21834987, PubMed : 23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CFL1
Research Areas : Neuroscience; Cancer; Cardiovasc µLar; Signal transduction