Volume : 50 µg
Clone Number :
Aliases : CCR4 associated factor 2 antibody; CCR4 NOT transcription complex subunit 2 antibody; CCR4-associated factor 2 antibody; CCR4-NOT transcription complex subunit 2 antibody; CDC36 antibody; CNOT2 antibody; CNOT2_HUMAN antibody; HSPC131 antibody; MSTP046 antibody; Negative reg µLator of transcription 2 antibody; NOT2 (negative reg µLator of transcription 2 yeast) homolog antibody; NOT2 antibody; NOT2H antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZN8
Immunogen : Recombinant Human CCR4-NOT transcription complex subunit 2 protein (1-335AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the CCR4-NOT complex which is one of the major cell µLar mRNA deadenylases and is linked to various cell µLar processes including b µLk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription reg µLation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional reg µLation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CNOT2
Research Areas : Others