Volume : 50 µg
Clone Number :
Aliases : ALBINISM OC µLAR TYPE I antibody; G protein coupled receptor 143 antibody; G-protein coupled receptor 143 antibody; GP143_HUMAN antibody; GPR143 antibody; MOA1 antibody; NETTLESHIP FALLS TYPE OC µLAR ALBINISM antibody; Oc µLar albinism type 1 protein antibody; Oc µLar albinism type 1 protein homolog antibody; Oc µLar albinism1 Nettleship Falls type antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51810
Immunogen : Recombinant Human G-protein coupled receptor 143 protein (314-404AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stim µLates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs thro µgh a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracell µLar G protein-coupled receptor involved in melanosome biogenesis, organization and transport.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GPR143
Research Areas : Neuroscience