HRP labelled

Volume : 50 µg
Clone Number :
Aliases : Beta transducin repeat containing E3 ubiquitin protein ligase antibody; beta TrCP1 antibody; beta-transducin repeat containing antibody; BETA-TRCP antibody; betaTrCP antibody; btrC antibody; bTrCP antibody; bTrCP1 antibody; E3RSIkappaB antibody; F box and WD repeat protein 1B antibody; F box and WD repeats protein beta TrCP antibody; F-box and WD repeats protein beta-TrCP antibody; F-box/WD repeat protein 1A antibody; F-box/WD repeat-containing protein 1A antibody; FBW1A antibody; FBW1A_HUMAN antibody; FBXW1 antibody; FBXW1A antibody; FWD1 antibody; HOS antibody; mKIAA4123 antibody; pIkappaBalpha-E3 receptor subunit antibody; Slimb antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y297
Immunogen : Recombinant Human F-box/WD repeat-containing protein 1A protein (397-448AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate recognition component of a SCF (SKP1-C µL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins. SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. Ubiquitination of NFKBIA occurs at \'Lys-21\' and \'Lys-22\'. SCF(BTRC) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed : 25704143, PubMed : 25503564). SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1/nuclear factor NF-kappa-B p105 subunit, ATF4, CDC25A, DLG1 FBXO5, PER1 SMAD3, SMAD4, SNAI1 and probably NFKB2. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2. May be involved in ubiquitination and subsequent proteasomal degradation thro µgh a DBB1-C µL4 E3 ubiquitin-protein ligase. Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1 IKBKB and TNF. Required for proteolytic processing of GLI3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTRC
Research Areas : Neuroscience; Cell biology; Microbiology

Volume : 50 µg
Clone Number :
Aliases : BTNL9 antibody; UNQ1900/PRO4346Butyrophilin-like protein 9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6UXG8
Immunogen : Recombinant Human Butyrophilin-like protein 9 protein (35-256AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTNL9
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : BTNL3 antibody; BTNL3_HUMAN antibody; BTNLR antibody; Butyrophilin like protein 3 antibody; Butyrophilin like receptor antibody; Butyrophilin-like protein 3 antibody; Butyrophilin-like receptor antibody; COLF4100 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6UXE8
Immunogen : Recombinant Human Butyrophilin-like protein 3 protein (18-237AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTNL3
Research Areas : Immunology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BTNL2Butyrophilin-like protein 2 antibody; BTL-II antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UIR0
Immunogen : Recombinant Human Butyrophilin-like protein 2 protein (26-202AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Negative reg µLator of T-cell proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTNL2
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : BT3A3_HUMAN antibody; BTF3 antibody; BTN3A3 antibody; Butyrophilin subfamily 3 member A3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00478
Immunogen : Recombinant Human Butyrophilin subfamily 3 member A3 protein (30-248AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays a role in T-cell responses in the adaptive immune response.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN3A3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BT3.2 antibody; BT3.3 antibody; BT3A2_HUMAN antibody; BTF4 antibody; BTN3A 2 antibody; BTN3A2 antibody; Butyrophilin protein antibody; Butyrophilin subfamily 3 member A2 antibody; Butyrophilin; subfamily 3; member A2 antibody; CD277 antibody; FLJ40011 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78410
Immunogen : Recombinant Human Butyrophilin subfamily 3 member A2 protein (30-248AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN3A2
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : BT3A1_HUMAN antibody; BTN3A1 antibody; Butyrophilin subfamily 3 member A1 antibody; CD277 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00481
Immunogen : Recombinant Human Butyrophilin subfamily 3 member A1 protein (30-254AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays a role in T-cell activation and in the adaptive immune response. Reg µLates the proliferation of activated T-cells. Reg µLates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN3A1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BT2.2 antibody; BT2A2_HUMAN antibody; BTF2 antibody; BTN2A2 antibody; butyrophilin 2 antibody; Butyrophilin subfamily 2 member A2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WVV5
Immunogen : Recombinant Human Butyrophilin subfamily 2 member A2 protein (33-262AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN2A2
Research Areas : Cancer; Cell biology; Immunology

Volume : 50 µg
Clone Number :
Aliases : BK14H9.1 antibody; BT2.1 antibody; BT2A1_HUMAN antibody; BTF1 antibody; BTN2A1 antibody; Butyrophilin BTF1 antibody; Butyrophilin subfamily 2 member A1 antibody; CTA-14H9.1 antibody; DJ3E1.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q7KYR7
Immunogen : Recombinant Human Butyrophilin subfamily 2 member A1 protein (29-248AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : extracell µLar exosome, integral component of plasma membrane, lipid metabolic process
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTN2A1
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Agammaglob µLinaemia tyrosine kinase antibody; AGMX 1 antibody; AGMX1 antibody; AT antibody; ATK antibody; B cell progenitor kinase antibody; B-cell progenitor kinase antibody; BPK antibody; Bruton agammaglob µLinemia tyrosine kinase antibody; Bruton tyrosine kinase antibody; Bruton?? Tyrosine Kinase antibody; Btk antibody; BTK_HUMAN antibody; dominant-negative kinase-deficient Brutons tyrosine kinase antibody; IMD 1 antibody; IMD1 antibody; MGC126261 antibody; MGC126262 antibody; OTTHUMP00000063593 antibody; PSCTK 1 antibody; PSCTK1 antibody; truncated Bruton agammaglob µLinemia tyrosine kinase antibody; Tyrosine protein kinase BTK antibody; Tyrosine-protein kinase BTK antibody; tyrosine-protein kinase BTK isoform (lacking exon 14 antibody; XLA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06187
Immunogen : Recombinant Human Tyrosine-protein kinase BTK protein (254-443AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that µLtimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway thro µgh calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molec µLe in reg µLating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription reg µLation. Induces the activity of NF-kappa-B, which is involved in reg µLating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind reg µLatory enhancer elements to mod µLate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the reg µLation of apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTK
Research Areas : Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B cell translocation gene 4 antibody; BTG family member 4 antibody; Btg4 antibody; BTG4_HUMAN antibody; MGC33003 antibody; PC3B antibody; Protein BTG4 antibody; Protein PC3b antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NY30
Immunogen : Recombinant Human Protein BTG4 protein (1-206AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Shows marked antiproliferative activity, being able to induce G(1) arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTG4
Research Areas : Cell biology