Volume : 50 µg
Clone Number :
Aliases : Ally of AML-1 and LEF-1 antibody; Ally of AML1 and LEF1 antibody; ALY antibody; ALY/REF antibody; Aly/REF export factor antibody; BEF antibody; bZIP enhancing factor antibody; bZIP-enhancing factor BEF antibody; REF antibody; THO complex 4 antibody; THO complex subunit 4 antibody; Tho4 antibody; thoc4 antibody; THOC4_HUMAN antibody; Transcriptional coactivator Aly/REF antibody; Transcriptional coactivator antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86V81
Immunogen : Recombinant Human THO complex subunit 4 protein (186-240AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is tho µght to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is tho µght to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\\\' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi\\\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production; ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALYREF
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Ally of AML-1 and LEF-1 antibody; Ally of AML1 and LEF1 antibody; ALY antibody; ALY/REF antibody; Aly/REF export factor antibody; BEF antibody; bZIP enhancing factor antibody; bZIP-enhancing factor BEF antibody; REF antibody; THO complex 4 antibody; THO complex subunit 4 antibody; Tho4 antibody; thoc4 antibody; THOC4_HUMAN antibody; Transcriptional coactivator Aly/REF antibody; Transcriptional coactivator antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86V81
Immunogen : Recombinant Human THO complex subunit 4 protein (186-240AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is tho µght to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is tho µght to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\\\' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi\\\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production; ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALYREF
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Ally of AML-1 and LEF-1 antibody; Ally of AML1 and LEF1 antibody; ALY antibody; ALY/REF antibody; Aly/REF export factor antibody; BEF antibody; bZIP enhancing factor antibody; bZIP-enhancing factor BEF antibody; REF antibody; THO complex 4 antibody; THO complex subunit 4 antibody; Tho4 antibody; thoc4 antibody; THOC4_HUMAN antibody; Transcriptional coactivator Aly/REF antibody; Transcriptional coactivator antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86V81
Immunogen : Recombinant Human THO complex subunit 4 protein (186-240AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is tho µght to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is tho µght to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\\\' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi\\\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production; ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALYREF
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Ally of AML-1 and LEF-1 antibody; Ally of AML1 and LEF1 antibody; ALY antibody; ALY/REF antibody; Aly/REF export factor antibody; BEF antibody; bZIP enhancing factor antibody; bZIP-enhancing factor BEF antibody; REF antibody; THO complex 4 antibody; THO complex subunit 4 antibody; Tho4 antibody; thoc4 antibody; THOC4_HUMAN antibody; Transcriptional coactivator Aly/REF antibody; Transcriptional coactivator antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86V81
Immunogen : SyntheVolumed peptide derived from the Internal region of Human ALY.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALYREF
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : THO complex 4
Aliases : Ally of AML 1 and LEF 1 ALY, BEF, bZIP enhancing factor BEF, THO complex 4, THO complex subunit 4, Tho4, THOC4
Observed MW : 32 kDa
Uniprot ID : Q86V81
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 200-1 : 1000
Gene ID :
Research Area : Neuroscience, Metabolism

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ALX4
GeneID : 60529
Uniprot : Q9H161
Specificity : ALX4 Antibody detects endogenous levels of ALX4.
Immunogen : A syntheVolumed peptide derived from human ALX4.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15628-BP
Des# Blocking Peptide : ALX4 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µL
Clone Number :
Aliases : ALX3Homeobox protein aristaless-like 3 antibody; Proline-rich transcription factor ALX3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95076
Immunogen : Recombinant Human Homeobox protein aristaless-like 3 protein (11-127AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcriptional reg µLator with a possible role in patterning of mesoderm during development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALX3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : ALX3Homeobox protein aristaless-like 3 antibody; Proline-rich transcription factor ALX3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95076
Immunogen : Recombinant Human Homeobox protein aristaless-like 3 protein (11-127AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptional reg µLator with a possible role in patterning of mesoderm during development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALX3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : ALX3Homeobox protein aristaless-like 3 antibody; Proline-rich transcription factor ALX3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95076
Immunogen : Recombinant Human Homeobox protein aristaless-like 3 protein (11-127AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcriptional reg µLator with a possible role in patterning of mesoderm during development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALX3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ALX3
GeneID : 257
Uniprot : O95076
Specificity : ALX3 Antibody detects endogenous levels of total ALX3.
Immunogen : A syntheVolumed peptide derived from human ALX3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835435
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3052-BP
Des# Blocking Peptide : ALX3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : ALX homeobox 1 antibody; ALX homeobox protein 1 antibody; ALX1 antibody; ALX1_HUMAN antibody; CART 1 antibody; CART-1 antibody; CART1 antibody; Cartilage homeoprotein 1 antibody; Cartilage paired class homeoprotein 1 antibody; FND3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15699
Immunogen : Recombinant Human ALX homeobox protein 1 protein (10-304AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed : 9753625, PubMed : 8756334). Most probably reg µLates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival (PubMed : 20451171). May also induce epithelial to mesenchymal transition (EMT) thro µgh the expression of SNAI1 (PubMed : 23288509).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALX1
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology; Stem cells