Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : BACE2
GeneID : 25825
Uniprot : Q9Y5Z0
Specificity : BACE2 Antibody detects endogenous levels of total BACE2.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13963-BP
Des# Blocking Peptide : BACE2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : APP beta secretase antibody; Asp 2 antibody; ASP2 antibody; Aspartyl protease 2 antibody; BACE 1 antibody; BACE antibody; BACE1 antibody; BACE1_HUMAN antibody; Beta secretase 1 antibody; Beta secretase antibody; Beta site amyloid beta A4 precursor protein cleaving enzyme antibody; Beta site amyloid precursor protein cleaving enzyme 1 antibody; Beta site amyloid precursor protein cleaving enzyme antibody; Beta site APP cleaving enzyme 1 antibody; Beta site APP cleaving enzyme antibody; Beta-secretase 1 antibody; Beta-site amyloid precursor protein cleaving enzyme 1 antibody; Beta-site APP cleaving enzyme 1 antibody; FLJ90568 antibody; HSPC104 antibody; Memapsin 2 antibody; Memapsin-2 antibody; Memapsin2 antibody; Membrane associated aspartic protease 2 antibody; Membrane-associated aspartic protease 2 antibody; Transmembrane aspartic proteinase Asp2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P56817
Immunogen : Recombinant Human Beta-secretase 1 protein (46-155AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracell µLar release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BACE1
Research Areas : Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : APP beta secretase antibody; Asp 2 antibody; ASP2 antibody; Aspartyl protease 2 antibody; BACE 1 antibody; BACE antibody; BACE1 antibody; BACE1_HUMAN antibody; Beta secretase 1 antibody; Beta secretase antibody; Beta site amyloid beta A4 precursor protein cleaving enzyme antibody; Beta site amyloid precursor protein cleaving enzyme 1 antibody; Beta site amyloid precursor protein cleaving enzyme antibody; Beta site APP cleaving enzyme 1 antibody; Beta site APP cleaving enzyme antibody; Beta-secretase 1 antibody; Beta-site amyloid precursor protein cleaving enzyme 1 antibody; Beta-site APP cleaving enzyme 1 antibody; FLJ90568 antibody; HSPC104 antibody; Memapsin 2 antibody; Memapsin-2 antibody; Memapsin2 antibody; Membrane associated aspartic protease 2 antibody; Membrane-associated aspartic protease 2 antibody; Transmembrane aspartic proteinase Asp2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P56817
Immunogen : Recombinant Human Beta-secretase 1 protein (46-155AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracell µLar release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BACE1
Research Areas : Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : APP beta secretase antibody; Asp 2 antibody; ASP2 antibody; Aspartyl protease 2 antibody; BACE 1 antibody; BACE antibody; BACE1 antibody; BACE1_HUMAN antibody; Beta secretase 1 antibody; Beta secretase antibody; Beta site amyloid beta A4 precursor protein cleaving enzyme antibody; Beta site amyloid precursor protein cleaving enzyme 1 antibody; Beta site amyloid precursor protein cleaving enzyme antibody; Beta site APP cleaving enzyme 1 antibody; Beta site APP cleaving enzyme antibody; Beta-secretase 1 antibody; Beta-site amyloid precursor protein cleaving enzyme 1 antibody; Beta-site APP cleaving enzyme 1 antibody; FLJ90568 antibody; HSPC104 antibody; Memapsin 2 antibody; Memapsin-2 antibody; Memapsin2 antibody; Membrane associated aspartic protease 2 antibody; Membrane-associated aspartic protease 2 antibody; Transmembrane aspartic proteinase Asp2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P56817
Immunogen : Recombinant Human Beta-secretase 1 protein (46-155AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracell µLar release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BACE1
Research Areas : Neuroscience; Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : BACE1
GeneID : 23621
Uniprot : P56817
Specificity : BACE1 Antibody detects endogenous levels of total BACE1.
Immunogen : A syntheVolumed peptide derived from human BACE1 corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841347
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7939-BP
Des# Blocking Peptide : BACE1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : BACE1
GeneID : 23621
Uniprot : P56817
Specificity : BACE Antibody detects endogenous levels of total BACE.
Immunogen : A syntheVolumed peptide derived from human BACE, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000, IF/ICC 1 : 100-1 : 500
Conj µgate : Unconj µgated
RRID : AB_2841085
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7594-BP
Des# Blocking Peptide : BACE Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : 6030405P19Rik antibody; AI429776 antibody; B830038C02Rik antibody; Brain and reproductive organ expressed (TNFRSF1A mod µLator) antibody; brain and reproductive organ expressed protein antibody; Brain and reproductive organ-expressed protein antibody; BRCA1 A complex subunit BRE antibody; BRCA1-A complex subunit BRE antibody; BRCA1/BRCA2 containing complex subunit 4 antibody; BRCA1/BRCA2 containing complex subunit 45 antibody; BRCA1/BRCA2-containing complex subunit 45 antibody; BRCC4 antibody; BRCC45 antibody; bre antibody; BRE_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NXR7
Immunogen : Recombinant Human BRISC and BRCA1-A complex member 2 protein (94-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the BRCA1-A complex, a complex that specifically recognizes \'Lys-63\'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes \'Lys-63\'-linked ubiquitin on histones H2A and H2AX (PubMed : 17525341 PubMed : 19261746, PubMed : 19261749, PubMed : 19261748). In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and mod µLating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer (PubMed : 21282113, PubMed : 19261748). Component of the BRISC complex, a m µLtiprotein complex that specifically cleaves \'Lys-63\'-linked ubiquitin in various substrates (PubMed : 19214193, PubMed : 24075985, PubMed : 25283148, PubMed : 26195665). Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity (PubMed : 21282113). The BRISC complex is required for normal mitotic spindle assembly and microtub µLe attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed : 26195665). The BRISC complex plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (PubMed : 24075985). Down-reg µLates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed : 24075985). May play a role in homeostasis or cell µLar differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway. May reg µLate TNF-alpha signaling thro µgh its interactions with TNFRSF1A; however these effects may be indirect (PubMed : 15465831).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BABAM2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 6030405P19Rik antibody; AI429776 antibody; B830038C02Rik antibody; Brain and reproductive organ expressed (TNFRSF1A mod µLator) antibody; brain and reproductive organ expressed protein antibody; Brain and reproductive organ-expressed protein antibody; BRCA1 A complex subunit BRE antibody; BRCA1-A complex subunit BRE antibody; BRCA1/BRCA2 containing complex subunit 4 antibody; BRCA1/BRCA2 containing complex subunit 45 antibody; BRCA1/BRCA2-containing complex subunit 45 antibody; BRCC4 antibody; BRCC45 antibody; bre antibody; BRE_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NXR7
Immunogen : Recombinant Human BRISC and BRCA1-A complex member 2 protein (94-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the BRCA1-A complex, a complex that specifically recognizes \'Lys-63\'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes \'Lys-63\'-linked ubiquitin on histones H2A and H2AX (PubMed : 17525341 PubMed : 19261746, PubMed : 19261749, PubMed : 19261748). In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and mod µLating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer (PubMed : 21282113, PubMed : 19261748). Component of the BRISC complex, a m µLtiprotein complex that specifically cleaves \'Lys-63\'-linked ubiquitin in various substrates (PubMed : 19214193, PubMed : 24075985, PubMed : 25283148, PubMed : 26195665). Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity (PubMed : 21282113). The BRISC complex is required for normal mitotic spindle assembly and microtub µLe attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed : 26195665). The BRISC complex plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (PubMed : 24075985). Down-reg µLates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed : 24075985). May play a role in homeostasis or cell µLar differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway. May reg µLate TNF-alpha signaling thro µgh its interactions with TNFRSF1A; however these effects may be indirect (PubMed : 15465831).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BABAM2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 6030405P19Rik antibody; AI429776 antibody; B830038C02Rik antibody; Brain and reproductive organ expressed (TNFRSF1A mod µLator) antibody; brain and reproductive organ expressed protein antibody; Brain and reproductive organ-expressed protein antibody; BRCA1 A complex subunit BRE antibody; BRCA1-A complex subunit BRE antibody; BRCA1/BRCA2 containing complex subunit 4 antibody; BRCA1/BRCA2 containing complex subunit 45 antibody; BRCA1/BRCA2-containing complex subunit 45 antibody; BRCC4 antibody; BRCC45 antibody; bre antibody; BRE_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NXR7
Immunogen : Recombinant Human BRISC and BRCA1-A complex member 2 protein (94-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the BRCA1-A complex, a complex that specifically recognizes \'Lys-63\'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes \'Lys-63\'-linked ubiquitin on histones H2A and H2AX (PubMed : 17525341 PubMed : 19261746, PubMed : 19261749, PubMed : 19261748). In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and mod µLating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer (PubMed : 21282113, PubMed : 19261748). Component of the BRISC complex, a m µLtiprotein complex that specifically cleaves \'Lys-63\'-linked ubiquitin in various substrates (PubMed : 19214193, PubMed : 24075985, PubMed : 25283148, PubMed : 26195665). Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity (PubMed : 21282113). The BRISC complex is required for normal mitotic spindle assembly and microtub µLe attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed : 26195665). The BRISC complex plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (PubMed : 24075985). Down-reg µLates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed : 24075985). May play a role in homeostasis or cell µLar differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway. May reg µLate TNF-alpha signaling thro µgh its interactions with TNFRSF1A; however these effects may be indirect (PubMed : 15465831).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BABAM2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 6030405P19Rik antibody; AI429776 antibody; B830038C02Rik antibody; Brain and reproductive organ expressed (TNFRSF1A mod µLator) antibody; brain and reproductive organ expressed protein antibody; Brain and reproductive organ-expressed protein antibody; BRCA1 A complex subunit BRE antibody; BRCA1-A complex subunit BRE antibody; BRCA1/BRCA2 containing complex subunit 4 antibody; BRCA1/BRCA2 containing complex subunit 45 antibody; BRCA1/BRCA2-containing complex subunit 45 antibody; BRCC4 antibody; BRCC45 antibody; bre antibody; BRE_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NXR7
Immunogen : Recombinant Human BRISC and BRCA1-A complex member 2 protein (94-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC, IF; Recommended dilution : IHC : 1 : 200-1 : 500, IF : 1 : 50-1 : 200
Background : Component of the BRCA1-A complex, a complex that specifically recognizes \\\'Lys-63\\\'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes \\\'Lys-63\\\'-linked ubiquitin on histones H2A and H2AX (PubMed : 17525341 PubMed : 19261746, PubMed : 19261749, PubMed : 19261748). In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and mod µLating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer (PubMed : 21282113, PubMed : 19261748). Component of the BRISC complex, a m µLtiprotein complex that specifically cleaves \\\'Lys-63\\\'-linked ubiquitin in various substrates (PubMed : 19214193, PubMed : 24075985, PubMed : 25283148, PubMed : 26195665). Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity (PubMed : 21282113). The BRISC complex is required for normal mitotic spindle assembly and microtub µLe attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed : 26195665). The BRISC complex plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (PubMed : 24075985). Down-reg µLates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed : 24075985). May play a role in homeostasis or cell µLar differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway. May reg µLate TNF-alpha signaling thro µgh its interactions with TNFRSF1A; however these effects may be indirect (PubMed : 15465831).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BABAM2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : FLJ20300 antibody; BAAT antibody; BAAT_HUMAN antibody; BACAT antibody; BAT antibody; Bile acid CoA : amino acid N-acyltransferase (glycine N-choloyltransferase) antibody; Bile acid CoA : amino acid N acyltransferase antibody; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody; Bile acid Coenzyme A : amino acid N acyltransferase antibody; Bile acid-CoA : amino acid N-acyltransferase antibody; Glycine N choloyltransferase antibody; Glycine N-choloyltransferase antibody; Long chain fatty acyl CoA hydrolase antibody; Long-chain fatty-acyl-CoA hydrolase antibody; MGC104432 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14032
Immunogen : Recombinant Human Bile acid-CoA : amino acid N-acyltransferase protein (313-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conj µgation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canalic µLi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic retic µLum (secondary bile acids). May catalyze the conj µgation of primary or secondary bile acids, or both. The conj µgation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconj µgated by bacteria in the intestine and are recycled back to the liver for reconj µgation (secondary bile acids). May also act as an acyl-CoA thioesterase that reg µLates intracell µLar levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conj µgates glycine to these acyl-CoAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BAAT
Research Areas : Cancer; Metabolism; Signal transduction