Volume : 50 µg
Clone Number :
Aliases : Activin A receptor antibody; Activin A receptor type II like 1 antibody; Activin A receptor; type II like kinase 1 antibody; Activin receptor like kinase 1 antibody; Activin receptor-like kinase 1 antibody; ACVL1_HUMAN antibody; ACVRL1 antibody; ACVRLK1 antibody; ALK-1 antibody; ALK1 antibody; HHT antibody; HHT2 antibody; ORW2 antibody; Osler Rendu Weber syndrome 2 antibody; Serine/threonine protein kinase receptor R3 antibody; Serine/threonine-protein kinase receptor R3 antibody; SKR3 antibody; TGF B superfamily receptor type I antibody; TGF-B superfamily receptor type I antibody; TSR-I antibody; TSR1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P37023
Immunogen : Recombinant Human Serine/threonine-protein kinase receptor R3 protein (22-118AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important reg µLator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional reg µLators. May bind activin as well.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACVRL1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Activin A receptor antibody; Activin A receptor type II like 1 antibody; Activin A receptor; type II like kinase 1 antibody; Activin receptor like kinase 1 antibody; Activin receptor-like kinase 1 antibody; ACVL1_HUMAN antibody; ACVRL1 antibody; ACVRLK1 antibody; ALK-1 antibody; ALK1 antibody; HHT antibody; HHT2 antibody; ORW2 antibody; Osler Rendu Weber syndrome 2 antibody; Serine/threonine protein kinase receptor R3 antibody; Serine/threonine-protein kinase receptor R3 antibody; SKR3 antibody; TGF B superfamily receptor type I antibody; TGF-B superfamily receptor type I antibody; TSR-I antibody; TSR1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P37023
Immunogen : Recombinant Human Serine/threonine-protein kinase receptor R3 protein (22-118AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important reg µLator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional reg µLators. May bind activin as well.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACVRL1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important reg µLator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional reg µLators. May bind activin as well.
Immunogen : activin A receptor type II-like 1
Aliases : Activin receptor like kinase 1 ACVRL1 ACVRLK1 ALK 1 ALK1 HHT, HHT2, ORW2, SKR3, TSR I
Observed MW : 56 kDa
Uniprot ID : P37023
Reactivity : Human
Application : ELISA, WB, IHC, FC, IP
Recommended dilution : WB : 1 : 200-1 : 1000; IHC : 1 : 100-1 : 400; IP : 1 : 200-1 : 1000
Gene ID : 94
Research Area : Cardiovasc µLar, Metabolism, Signal Transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ACVR2B
GeneID : 93
Uniprot : Q13705
Specificity : ACVR2B Antibody detects endogenous levels of total ACVR2B.
Immunogen : A syntheVolumed peptide derived from human ACVR2B, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Dog,Chicken,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842342
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF9146-BP
Des# Blocking Peptide : ACVR2B Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ACVR2A
GeneID : 92
Uniprot : P27037
Specificity : ACVR2A Antibody detects endogenous levels of total ACVR2A.
Immunogen : A syntheVolumed peptide derived from human ACVR2A, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838695
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6733-BP
Des# Blocking Peptide : ACVR2A Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ACVR1C
GeneID : 130399
Uniprot : Q8NER5
Specificity : ACVR1C Antibody detects endogenous levels of total ACVR1C.
Immunogen : A syntheVolumed peptide derived from human ACVR1C, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838085
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6118-BP
Des# Blocking Peptide : ACVR1C Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Activin A receptor type 1B antibody; Activin A receptor type II like kinase 4 antibody; Activin A type 1B receptor antibody; Activin A type IB receptor antibody; Activin receptor like kinase 4 antibody; Activin receptor type 1B antibody; Activin receptor type IB antibody; Activin receptor type-1B antibody; Activin receptor-like kinase 4 antibody; ACTR IB antibody; ACTR-IB antibody; ACTRIB antibody; ACV1B_HUMAN antibody; ACVR 1B antibody; Acvr1b antibody; ACVRLK 4 antibody; ACVRLK4 antibody; ALK 4 antibody; ALK-4 antibody; ALK4 antibody; Serine(threonine) protein kinase receptor R2 antibody; Serine/threonine-protein kinase receptor R2 antibody; SKR 2 antibody; SKR2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P36896
Immunogen : Recombinant Human Activin receptor type-1B protein (150-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus reg µLating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracell µLar matrix production, immunosuppression and carcinogenesis. Activin is also tho µght to have a paracrine or autocrine role in follic µLar development in the ovary. Within the receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a primary activin receptors whereas the type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor such as ACVR1B. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B thro µgh FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor. ACVR1B also phosphorylates TDP2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACVR1B
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Activin A receptor type 1B antibody; Activin A receptor type II like kinase 4 antibody; Activin A type 1B receptor antibody; Activin A type IB receptor antibody; Activin receptor like kinase 4 antibody; Activin receptor type 1B antibody; Activin receptor type IB antibody; Activin receptor type-1B antibody; Activin receptor-like kinase 4 antibody; ACTR IB antibody; ACTR-IB antibody; ACTRIB antibody; ACV1B_HUMAN antibody; ACVR 1B antibody; Acvr1b antibody; ACVRLK 4 antibody; ACVRLK4 antibody; ALK 4 antibody; ALK-4 antibody; ALK4 antibody; Serine(threonine) protein kinase receptor R2 antibody; Serine/threonine-protein kinase receptor R2 antibody; SKR 2 antibody; SKR2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P36896
Immunogen : Recombinant Human Activin receptor type-1B protein (150-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus reg µLating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracell µLar matrix production, immunosuppression and carcinogenesis. Activin is also tho µght to have a paracrine or autocrine role in follic µLar development in the ovary. Within the receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a primary activin receptors whereas the type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor such as ACVR1B. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B thro µgh FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor. ACVR1B also phosphorylates TDP2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACVR1B
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Activin A receptor type 1B antibody; Activin A receptor type II like kinase 4 antibody; Activin A type 1B receptor antibody; Activin A type IB receptor antibody; Activin receptor like kinase 4 antibody; Activin receptor type 1B antibody; Activin receptor type IB antibody; Activin receptor type-1B antibody; Activin receptor-like kinase 4 antibody; ACTR IB antibody; ACTR-IB antibody; ACTRIB antibody; ACV1B_HUMAN antibody; ACVR 1B antibody; Acvr1b antibody; ACVRLK 4 antibody; ACVRLK4 antibody; ALK 4 antibody; ALK-4 antibody; ALK4 antibody; Serine(threonine) protein kinase receptor R2 antibody; Serine/threonine-protein kinase receptor R2 antibody; SKR 2 antibody; SKR2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P36896
Immunogen : Recombinant Human Activin receptor type-1B protein (150-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus reg µLating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracell µLar matrix production, immunosuppression and carcinogenesis. Activin is also tho µght to have a paracrine or autocrine role in follic µLar development in the ovary. Within the receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a primary activin receptors whereas the type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor such as ACVR1B. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B thro µgh FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor. ACVR1B also phosphorylates TDP2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACVR1B
Research Areas : Signal transduction; Stem cells

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2(ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus reg µLating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracell µLar matrix production, immunosuppression and carcinogenesis. Activin is also tho µght to have a paracrine or autocrine role in follic µLar development in the ovary. Within the receptor complex, type-2 receptors(ACVR2A and/or ACVR2B) act as a primary activin receptors whereas the type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor such as ACVR1B. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B thro µgh FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor. ACVR1B also phosphorylates TDP2.
Immunogen : activin A receptor, type IB
Aliases : Activin A receptor, type IB, Activin receptor like kinase 4, Activin receptor type 1B, Activin receptor type IB, ACTR IB, ACTRIB, ACVR1B, ACVRLK4, ALK 4, ALK4, SKR2
Observed MW : 50 kDa-70 kDa
Uniprot ID : P36896
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 200-1 : 2000; IHC : 1 : 20-1 : 200
Gene ID : 91
Research Area : Stem Cells, Signal Transduction, Metabolism

Volume : 50 µL
Clone Number :
Aliases : Activin A receptor type I antibody; Activin A receptor type II like kinase 2 antibody; Activin receptor type I antibody; Activin receptor type-1 antibody; Activin receptor-like kinase 2 antibody; ACTR-I antibody; ACTRI antibody; Acvr1 antibody; ACVR1_HUMAN antibody; ACVR1A antibody; ACVRLK2 antibody; ALK 2 antibody; ALK-2 antibody; ALK2 antibody; FOP antibody; Hydroxyalkyl protein kinase antibody; Serine/threonine-protein kinase receptor R1 antibody; SKR1 antibody; TGF-B superfamily receptor type I antibody; TGFB superfamily receptor type I antibody; TSR-I antibody; TSRI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q04771
Immunogen : Recombinant Human Activin receptor type-1 protein (20-125AA)
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB, IHC, IF; Recommended dilution : WB : 1 : 500-1 : 2000, IHC : 1 : 20-1 : 200, IF : 1 : 50-1 : 200
Background : On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional reg µLators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis .
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACVR1
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction; Stem cells