Volume : 50 µg
Clone Number :
Aliases : 2310007D09Rik antibody; BB104611 antibody; C20orf129 antibody; CHICA antibody; dJ616B8.3 antibody; FA83D antibody; FA83D_HUMAN antibody; FAM83D antibody; Family with sequence similarity 83; member D antibody; FLJ38341 antibody; MGC92947 antibody; Protein FAM83D antibody; RGD1565583 antibody; RP23-119H5.1 antibody; Spindle protein CHICA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H4H8
Immunogen : Recombinant Human Protein FAM83D protein (339-470AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable proto-oncogene that reg µLates cell proliferation, growth, migration and epithelial to mesenchymal transition. Thro µgh the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed : 24344117). May play also a role in cell proliferation thro µgh activation of the ERK1/ERK2 signaling cascade (PubMed : 25646692). May also be important for proper chromosome congression and alignment during mitosis thro µgh its interaction with KIF22.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FAM83D
Research Areas : Epigenetics and Nuclear Signaling; Cancer