Volume : 50 µg
Clone Number :
Aliases : DKFZp686E20226 antibody; FLJ42187 antibody; High mobility group nucleosomal binding domain 3 antibody; High mobility group nucleosome-binding domain-containing protein 3 antibody; HMGN3 antibody; HMGN3_HUMAN antibody; OTTHUMP00000016772 antibody; OTTHUMP00000016773 antibody; PNAS 24 antibody; PNAS 25 antibody; PNAS24 antibody; PNAS25 antibody; Thyroid hormone receptor interacting protein 7 antibody; Thyroid receptor-interacting protein 7 antibody; TR-interacting protein 7 antibody; TRIP 7 antibody; TRIP-7 antibody; TRIP7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15651
Immunogen : Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds to nucleosomes, reg µLating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both ins µLin and glucagon levels and mod µLates the expression of pancreatic genes involved in ins µLin secretion. Reg µLates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Reg µLates the expression of SLC6A9, a glycine transporter which reg µLates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in oc µLar development and astrocyte function (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGN3
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction