Biotinilated

Volume : 50 µL
Clone Number :
Aliases : CASTOR2 antibody; Cell µLar arginine sensor for mTORC1 protein 2 antibody; GATL2_HUMAN antibody; GATS-like protein 2 antibody; GATSL2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A6NHX0
Immunogen : Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions as a negative reg µLator of the TORC1 signaling pathway thro µgh the GATOR complex. As part of homodimers or heterodimers with CASTOR1 directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASTOR2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BS 17 antibody; Calpain inhibitor antibody; Calpastatin antibody; Cast antibody; Heart type calpastatin antibody; ICAL_HUMAN antibody; MGC9402 antibody; Sperm BS 17 component antibody; Sperm BS-17 component antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20810
Immunogen : Recombinant Human Calpastatin protein (1-667AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CAST
Research Areas : Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Ca sensing receptor antibody; Ca2+ sensing receptor 1 antibody; Ca2+ sensing receptor antibody; Calcium sensing receptor antibody; CAR antibody; CaSR antibody; CASR_HUMAN antibody; EIG8 antibody; Extracell µLar calcium sensing receptor antibody; Extracell µLar calcium sensing receptor [Precursor] antibody; Extracell µLar calcium-sensing receptor antibody; FHH antibody; FIH antibody; GPRC2A antibody; HHC antibody; HHC1 antibody; Hypocalciuric hypercalcemia 1 antibody; Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody; MGC138441 antibody; NSHPT antibody; Parathyroid Ca(2+) sensing receptor 1 antibody; Parathyroid Cell calcium sensing receptor antibody; Parathyroid Cell calcium-sensing receptor antibody; PCAR 1 antibody; PCaR1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P41180
Immunogen : Recombinant Human Extracell µLar calcium-sensing receptor protein (20-612AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Senses changes in the extracell µLar concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASR
Research Areas : Neuroscience; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AA033488 antibody; AW146219 antibody; Calsequestrin 2 (cardiac muscle) antibody; Calsequestrin 2 fast twitch cardiac muscle antibody; Calsequestrin antibody; Calsequestrin cardiac muscle isoform antibody; Calsequestrin fast twitch cardiac muscle antibody; Calsequestrin-2 antibody; Calsequestrin2 antibody; cardCSQ antibody; Cardiac calsequestrin 2 antibody; cardiac muscle isoform antibody; CASQ 2 antibody; CASQ2 antibody; CASQ2_HUMAN antibody; cCSQ antibody; ESTM52 antibody; FLJ26321 antibody; FLJ93514 antibody; PDIB2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14958
Immunogen : Recombinant Human Calsequestrin-2 protein (219-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Reg µLates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in reg µLating the rate of heart beats.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASQ2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Calmitin antibody; Calmitine antibody; Calsequestrin 1 (fast twitch; skeletal muscle) antibody; Calsequestrin antibody; Calsequestrin; cell antibody; Calsequestrin; skeletal muscle isoform antibody; Calsequestrin-1 antibody; CASQ antibody; Casq1 antibody; CASQ1_HUMAN antibody; PDIB1 antibody; skeletal muscle isoform antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31415
Immunogen : Recombinant Human Calsequestrin-1 protein (127-396AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Reg µLates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASQ1
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : APAF-3 antibody; Apoptotic protease Mch-6 antibody; Apoptotic protease-activating factor 3 antibody; CASP-9 antibody; CASP9 antibody; CASP9_HUMAN antibody; Caspase 9 antibody; Caspase-9 subunit p10 antibody; ICE-LAP6 antibody; ICE-like apoptotic protease 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55211
Immunogen : Recombinant Human Caspase-9 protein (113-324AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP9
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : ALPS2B antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein antibody; Apoptosis related cysteine peptidase antibody; Apoptotic cysteine protease antibody; Apoptotic protease Mch-5 antibody; Apoptotic protease Mch5 antibody; CAP 4 antibody; CAP4 antibody; CASP-8 antibody; CASP8 antibody; CASP8_HUMAN antibody; Caspase 8 antibody; Caspase 8 apoptosis related cysteine peptidase antibody; Caspase IIX antibody; Caspase-8 subunit p10 antibody; caspase8 antibody; CED 3 antibody; FADD Homologous ICE/CED3 Like Protease antibody; FADD Like ICE antibody; FADD-homologous ICE/CED-3-like protease antibody; FADD-like ICE antibody; FLICE antibody; FLJ17672 antibody; ICE-like apoptotic protease 5 antibody; MACH alpha 1/2/3 protein antibody; MACH antibody; MACH beta 1/2/3/4 protein antibody; MACH5 antibody; MCH 5 antibody; MCH5 antibody; MGC78473 antibody; MORT1 associated ced 3 homolog antibody; MORT1 associated CED3 homolog antibody; MORT1-associated CED-3 homolog antibody; OTTHUMP00000163717 antibody; OTTHUMP00000163720 antibody; OTTHUMP00000163724 antibody; OTTHUMP00000163725 antibody; OTTHUMP00000165062 antibody; OTTHUMP00000165063 antibody; OTTHUMP00000165064 antibody; OTTHUMP00000206552 antibody; OTTHUMP00000206582 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14790
Immunogen : Recombinant Human Caspase-8 protein (217-374AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molec µLe FADD recruits it to either receptor. The res µLting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molec µLe substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP8
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : apoptosis-related cysteine peptidase antibody; Apoptotic protease Mch-3 antibody; CASP-7 antibody; CASP7 antibody; CASP7_HUMAN antibody; Caspase-7 subunit p11 antibody; CMH-1 antibody; ICE-LAP3 antibody; ICE-like apoptotic protease 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55210
Immunogen : Recombinant Human Caspase-7 protein (24-198AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP7
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Apoptotic protease Mch-2 antibody; Apoptotic protease MCH2 antibody; CASP-6 antibody; CASP6 antibody; CASP6_HUMAN antibody; Caspase 6 antibody; Caspase 6 apoptosis related cysteine protease antibody; Caspase 6; apoptosis related cysteine peptidase antibody; Caspase-6 antibody; Caspase-6 subunit p11 antibody; Mch2 antibody; OTTHUMP00000162742 antibody; OTTHUMP00000162743 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55212
Immunogen : Recombinant Human Caspase-6 protein (24-293AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP6
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Apoptosis related cysteine protease antibody; CASP-5 antibody; CASP5 antibody; CASP5_HUMAN antibody; Caspase-5 subunit p10 antibody; ICE(rel)-III antibody; ICERELIII antibody; ICH 3 antibody; ICH 3 protease antibody; Protease ICH-3 antibody; Protease TY antibody; TY antibody; TY protease antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51878
Immunogen : Recombinant Human Caspase-5 protein (137-327AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Mediator of programmed cell death (apoptosis).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP5
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Apoptotic cysteine protease Mih1/TX antibody; CASP-4 antibody; CASP4 antibody; CASP4_HUMAN antibody; Caspase 4 apoptosis related cysteine peptidase antibody; Caspase-4 subunit 2 antibody; Caspase4 antibody; ICE(rel)-II antibody; ICE(rel)II antibody; ICEREL II antibody; ICH2 antibody; Mih1/TX antibody; Protease ICH-2 antibody; Protease TX antibody; TX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49662
Immunogen : Recombinant Human Caspase-4 protein (82-226AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inflammatory caspase (PubMed : 7797510, PubMed : 23516580, PubMed : 25119034). Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS (PubMed : 22246630, PubMed : 26174085, PubMed : 26173988, PubMed : 26508369, PubMed : 25964352). Independently of NLRP3 inflammasome and CASP1 promotes pyroptosis, thro µgh GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators (PubMed : 24879791 PubMed : 25964352). Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic epithelial cells during infection (PubMed : 25121752). In later stages of the infection, LPS from cytosolic Salmonella triggers CASP4 activation, which µLtimately res µLts in pyroptosis of infected cells and their extrusion into the gut lumen, as well as in IL18 secretion. Pyroptosis limits bacterial replication, while cytokine secretion promotes the recruitment and activation of immune cells and triggers mucosal inflammation. Involved in LPS-induced IL6 secretion; this activity may not require caspase enzymatic activity (PubMed : 26508369). Involved in cell death induced by endoplasmic retic µLum stress and by treatment with cytotoxic APP peptides found Alzheimer\'s patient brains (PubMed : 15123740, PubMed : 22246630, PubMed : 23661706). Activated by direct binding to LPS without the need of an upstream sensor (PubMed : 25119034). Does not directly process IL1B (PubMed : 7743998, PubMed : 7797592, PubMed : 7797510).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP4
Research Areas : Cancer; Cell biology; Metabolism