FITC

Volume : 50 µg
Clone Number :
Aliases : DAP kinase 3 antibody; DAP like kinase antibody; DAP-like kinase antibody; Dapk 3 antibody; DAPK3 antibody; DAPK3_HUMAN antibody; Death associated kinase 3 antibody; Death associated protein kinase 3 antibody; Death-associated protein kinase 3 antibody; Dlk antibody; EC 2.7.11.1 antibody; FLJ36473 antibody; MYPT1 kinase antibody; ZIP antibody; ZIP kinase antibody; ZIP kinase isoform antibody; ZIP-kinase antibody; ZIPK antibody; zipper-interacting protein kinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43293
Immunogen : Recombinant Human Death-associated protein kinase 3 protein (283-401AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which is involved in the reg µLation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the reg µLation of smooth muscle contraction. Reg µLates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cell µLar setting. Involved in reg µLation of starvation-induced autophagy. Reg µLates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, reg µLates myosin either directly by phosphorylating MYL12B and MYL9 or thro µgh inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A; the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca(2+) and promote a contractile state. Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton. Isoform 2 can phosphorylate myosin, PPP1R12A and MYL12B. Overexpression leads to condensation of actin stress fibers into thick bundles. Involved in actin filament focal adhesion dynamics. The function in both reorganization of actin cytoskeleton and focal adhesion dissolution is mod µLated by RhoD. Positively reg µLates canonical Wnt/beta-catenin signaling thro µgh interaction with NLK and TCF7L2. Phosphorylates RPL13A on \'Ser-77\' upon interferon-gamma activation which is causing RPL13A release from the ribosome, RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Involved in reg µLation of cell cycle progression and cell proliferation. May be a tumor suppressor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAPK3
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DAK2 antibody; DAP kinase 2 antibody; DAP kinase related protein 1 antibody; DAP kinase related protein 1 beta isoform antibody; DAP-kinase-related protein 1 antibody; DAPK2 antibody; DAPK2_HUMAN antibody; Death associated protein kinase 2 antibody; Death-associated protein kinase 2 antibody; DRP 1 antibody; DRP-1 antibody; DRP1 antibody; MGC119312 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UIK4
Immunogen : Recombinant Human Death-associated protein kinase 2 protein (222-370AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Calcium/calmod µLin-dependent serine/threonine kinase involved in m µLtiple cell µLar signaling pathways that trigger cell survival, apoptosis, and autophagy. Reg µLates both type I apoptotic and type II autophagic cell deaths signal, depending on the cell µLar setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accum µLation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in gran µLocytic maturation. Isoform 2 is not reg µLated by calmod µLin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAPK2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DAP 1 antibody; Dap antibody; DAP-1 antibody; DAP1_HUMAN antibody; Death associated protein 1 antibody; Death associated protein antibody; Death-associated protein 1 antibody; MGC99796 antibody; OTTHUMP00000161670 antibody; OTTHUMP00000221331 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51397
Immunogen : Recombinant Human Death-associated protein 1 protein (2-102AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in mediating interferon-gamma-induced cell death.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAP
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : D-amino acid oxidase activator antibody; DAOA antibody; DAOA_HUMAN antibody; G72 transcript antibody; LG72 antibody; Protein G72 antibody; Schizophrenia and bipolar disorder associated protein G72 antibody; SG72 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P59103
Immunogen : Recombinant Human D-amino acid oxidase activator protein (1-153AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAOA
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : D-amino-acid oxidase antibody; DAAO antibody; DAMOX antibody; DAO antibody; DAO1 antibody; EC 1.4.3.3 antibody; MGC35381 antibody; OXDA antibody; OXDA_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P14920
Immunogen : Recombinant Human D-amino-acid oxidase protein (1-347AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Reg µLates the level of the neuromod µLator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Co µLd act as a detoxifying agent which removes D-amino acids accum µLated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAO
Research Areas : Tags & Cell Markers; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BMP antagonist 3 antibody; CER2 antibody; cerberus 2 antibody; Cerberus like 2 antibody; Cerberus-like protein 2 antibody; Cerl-2 antibody; CERL2 antibody; CKTSF1B3 antibody; COCO antibody; CRL2 antibody; Cysteine knot superfamily 1 antibody; Cysteine knot superfamily 1 BMP antagonist 3 antibody; DAN domain family member 5 antibody; Dand5 antibody; DAND5_HUMAN antibody; DANTE antibody; GREM3 antibody; Gremlin-3 antibody; MGC126849 antibody; SP1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N907
Immunogen : Recombinant Human DAN domain family member 5 protein (23-189AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Seems to play a role in the correct specification of the left-right axis. May antagonize NODAL and BMP4 signaling. Cystine knot-containing proteins play important roles during development, organogenesis, tissue growth and differentiation (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAND5
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DALRD3DALR anticodon-binding domain-containing protein 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5D0E6
Immunogen : Recombinant Human DALR anticodon-binding domain-containing protein 3 protein (182-481AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DALRD3
Research Areas : Epigenetics and Nuclear Signaling; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 156DAG antibody; A3a antibody; AGRNR antibody; Alpha dystroglycan antibody; Alpha-DG antibody; Beta-DG antibody; Beta-dystroglycan antibody; DAG antibody; Dag1 antibody; DAG1_HUMAN antibody; Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody; Dystroglycan antibody; Dystrophin associated glycoprotein 1 antibody; Dystrophin-associated glycoprotein 1 antibody; OTTHUMP00000210857 antibody; OTTHUMP00000210858 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14118
Immunogen : Peptide sequence from Human Dystroglycan protein (726-744AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAG1
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DAD 1 antibody; DAD-1 antibody; dad1 antibody; DAD1_HUMAN antibody; Defender against cell death 1 antibody; Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody; Oligosaccharyl transferase subunit DAD1 antibody; OST 2 antibody; OST2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P61803
Immunogen : Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein (1-113AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed : 22467853). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic retic µLum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis (PubMed : 22467853).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAD1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Dact antibody; dact1 antibody; DACT1_HUMAN antibody; Dapper antagonist of beta catenin homolog 1 antibody; Dapper antagonist of catenin 1 antibody; Dapper antibody; Dapper homolog 1 antibody; DAPPER1 antibody; Dpr antibody; Dpr1 antibody; Frd antibody; Frodo antibody; hDPR1 antibody; Hepatocell µLar carcinoma novel gene 3 protein antibody; Heptacell µLar carcinoma novel gene 3 antibody; HNG3 antibody; MTNG3 antibody; Thyex3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYF0
Immunogen : Recombinant Human Dapper homolog 1 protein (410-525AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in reg µLation of intracell µLar signaling pathways during development. Specifically tho µght to play a role in canonical and/or non-canonical Wnt signaling pathways thro µgh interaction with DSH (Dishevelled) family proteins. The activation/inhibition of Wnt signaling may depend on the phosphorylation status. Proposed to reg µLate the degradation of CTNNB1/beta-catenin, thereby mod µLating the transcriptional activation of target genes of the Wnt signaling pathway. Its function in stabilizing CTNNB1 may involve inhibition of GSK3B activity. Promotes the membrane localization of CTNNB1. The cytoplasmic form can induce DVL2 degradation via a lysosome-dependent mechanism; the function is inhibited by PKA-induced binding to 14-3-3 proteins, such as YWHAB. Seems to be involved in morphogenesis at the primitive streak by reg µLating VANGL2 and DVL2; the function seems to be independent of canonical Wnt signaling and rather involves the non-canonical Wnt/planar cell polarity (PCP) pathway (By similarity). The nuclear form may prevent the formation of LEF1 : CTNNB1 complex and recruit HDAC1 to LEF1 at target gene promoters to repress transcription thus antagonizing Wnt signaling. May be involved in positive reg µLation of fat cell differentiation. During neuronal differentiation may be involved in excitatory synapse organization, and dendrite formation and establishment of spines.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DACT1
Research Areas : Neuroscience; Stem cells

Volume : 50 µg
Clone Number :
Aliases : DACH antibody; Dach1 antibody; DACH1_HUMAN antibody; Dachshund family transcription factor 1 antibody; dachshund homolog 1 (Drosophila) antibody; Dachshund homolog 1 antibody; Dachsund homolog 1 antibody; FLJ10138 antibody; OTTHUMP00000018494 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UI36
Immunogen : Recombinant Human Dachshund homolog 1 protein (166-369AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor that is involved in reg µLation of organogenesis. Seems to be a reg µLator of SIX1 SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation thro µgh recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in reg µLating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling thro µgh interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DACH1
Research Areas : Epigenetics and Nuclear Signaling; Cancer