FITC

Volume : 50 µg
Clone Number :
Aliases : 2.5Single-stranded DNA-binding protein gp2.5 antibody; SSB protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Enterobacteria phage T7 (Bacteriophage T7)
UniProt ID : P03696
Immunogen : Recombinant Enterobacteria phage T7 Single-stranded DNA-binding protein gp2.5 protein (1-232AA)
Raised in : Rabbit
Species Reactivity : Enterobacteria phage T7
Tested Applications :
Background : Single-stranded DNA-binding protein that eliminates secondary structure in long ssDNA formed on the lagging strand of the replication fork. Stim µLates DNA polymerase activity and increases the efficiency of RNA primer synthesis by interacting with the DNA polymerase and the helicase/primase protein gp4. Disrupts loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : 2.5
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : MASP1 antibody; CRARF antibody; CRARF1 antibody; PRSS5Mannan-binding lectin serine protease 1 antibody; EC 3.4.21.- antibody; Complement factor MASP-3 antibody; Complement-activating component of Ra-reactive factor antibody; Mannose-binding lectin-associated serine protease 1 antibody; MASP-1 antibody; Mannose-binding protein-associated serine protease antibody; Ra-reactive factor serine protease p100 antibody; RaRF antibody; Serine protease 5) [Cleaved into : Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P48740
Immunogen : Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens thro µgh patterns of s µgar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to s µgar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MASP1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : dJ994E9.2 antibody; MAS L antibody; MAS R antibody; Mas related G protein coupled MRG antibody; Mas related G protein coupled receptor antibody; MAS-R antibody; Mas-related G-protein coupled receptor MRG antibody; MAS1 oncogene like antibody; MAS1 proto-oncogene like; G protein-coupled receptor antibody; MAS1-like antibody; MAS1L antibody; MAS1L_HUMAN antibody; MGC119987 antibody; MRG antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35410
Immunogen : Recombinant Human Mas-related G-protein coupled receptor MRG protein (318-378AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : cytoplasm, integral component of membrane, integral component of plasma membrane, nucleoplasm, plasma membrane, G-protein coupled receptor activity, G-protein coupled receptor signaling pathway
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAS1L
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : MAS antibody; MAS proto oncogene antibody; Mas-related G protein-coupled receptor A antibody; MAS_HUMAN antibody; Mas1 antibody; MAS1 oncogene antibody; MAS1 proto-oncogene; G protein-coupled receptor antibody; MGRA antibody; Proto-oncogene Mas antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04201
Immunogen : Recombinant Human Proto-oncogene Mas protein (285-325AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), altho µgh it up-reg µLates AGTR1 receptor levels. Positive reg µLation of AGTR1 levels occurs thro µgh activation of the G-proteins GNA11 and GNAQ, and stim µLation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAS1
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ32280 antibody; MALD3_HUMAN antibody; MARVD3 antibody; MARVEL (membrane associating) domain containing 3 antibody; MARVEL domain containing 3 antibody; MARVEL domain-containing protein 3 antibody; MARVELD3 antibody; MRVLDC3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96A59
Immunogen : Recombinant Human MARVEL domain-containing protein 3 protein (1-189AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : As a component of tight junctions, plays a role in paracell µLar ion conductivity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MARVELD3
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : mars2 antibody; Methionine tRNA ligase 2 antibody; Methionine tRNA ligase 2 mitochondrial antibody; Methionine tRNA ligase antibody; Methionine tRNA synthetase 2 antibody; Methionine--tRNA ligase antibody; Methionyl tRNA synthetase 2 mitochondrial antibody; Methionyl tRNA synthetase mitochondrial antibody; Methionyl-tRNA synthetase 2 antibody; MetRS antibody; mitochondrial antibody; Mitochondrial methionine tRNA ligase antibody; Mitochondrial methionyl tRNA synthetase antibody; Mitochondrial methionyl-tRNA synthetase antibody; MtMetRS antibody; SYMM_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96GW9
Immunogen : Recombinant Human Methionine--tRNA ligase, mitochondrial protein (225-460AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MARS2
Research Areas : Epigenetics and Nuclear Signaling; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C-TAK1 antibody; Cdc25C associated protein kinase 1 antibody; Cdc25C-associated protein kinase 1 antibody; cTAK1 antibody; ELKL motif kinase 2 antibody; EMK-2 antibody; Emk2 antibody; ETK 1 antibody; KIAA4230 antibody; KP78 antibody; MAP microtub µLe affinity reg µLating kinase 3 antibody; MAP/microtub µLe affinity-reg µLating kinase 3 antibody; Mark3 antibody; MARK3_HUMAN antibody; Par 1a antibody; PAR1A antibody; Protein kinase STK10 antibody; Ser/Thr protein kinase PAR-1 antibody; Serine threonine protein kinase p78 antibody; Serine/threonine-protein kinase p78 antibody; SerThr protein kinase PAR 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P27448
Immunogen : Recombinant Human MAP/microtub µLe affinity-reg µLating kinase 3 protein (368-667AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the specific phosphorylation of microtub µLe-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on \'Ser-216\'. Reg µLates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MARK3
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ELKL motif kinase 1 antibody; ELKL motif kinase antibody; EMK-1 antibody; EMK1 antibody; MAP/microtub µLe affinity reg µLating kinase 2 antibody; MAP/microtub µLe affinity-reg µLating kinase 2 antibody; Mark2 antibody; MARK2_HUMAN antibody; MGC99619 antibody; PAR 1 antibody; Par 1b antibody; PAR1 homolog antibody; Par1b antibody; Ser/Thr protein kinase PAR 1B antibody; Serine/threonine protein kinase EMK antibody; Serine/threonine protein kinase MARK2 antibody; Serine/threonine-protein kinase MARK2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q7KZI7
Immunogen : Recombinant Human Serine/threonine-protein kinase MARK2 protein (373-594AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in cell polarity and microtub µLe dynamics reg µLation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtub µLe-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtub µLes, and their disassembly. Reg µLates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the reg µLation of neuronal migration thro µgh its dual activities in reg µLating cell µLar polarity and microtub µLe dynamics, possibly by phosphorylating and reg µLating DCX. Reg µLates axogenesis by phosphorylating KIF13B, promoting interaction between KIF13B and 14-3-3 and inhibiting microtub µLe-dependent accum µLation of KIF13B. Also required for neurite outgrowth and establishment of neuronal polarity. Reg µLates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Also acts as a positive reg µLator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1 DVL2 and/or DVL3). Mod µLates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MARK2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AURKC antibody; AIE 2 antibody; Aie1 antibody; AIE2 antibody; AIK 3 antibody; AIK3 antibody; ARK 3 antibody; ARK-3 antibody; ARK3 antibody; Aur C antibody; AurC antibody; Aurkc antibody; AURKC_HUMAN antibody; aurora 3 antibody; Aurora C antibody; Aurora kinase C antibody; aurora related kinase 3 antibody; Aurora-related kinase 3 antibody; Aurora/Ipl1 related kinase 3 antibody; Aurora/Ipl1-related kinase 3 antibody; Aurora/Ipl1/Eg2 protein 2 antibody; EC 2.7.11.1 antibody; Serine threonine protein kinase 13 antibody; serine/threonine kinase 13 (aurora/IPL1 like) antibody; serine/threonine protein kinase aurora C antibody; Serine/threonine-protein kinase 13 antibody; Serine/threonine-protein kinase aurora-C antibody; SPGF5 antibody; STK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQB9
Immunogen : Recombinant Human Aurora kinase C protein (12-143AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key reg µLator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtub µLe stabilization and spindle assembly. Plays also a role in meiosis and more partic µLarly in spermatogenesis. Has redundant cell µLar functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at \'Ser-10\' and \'Ser-28\'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1 another protein involved in cell division, at \'Ser-228\'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKC
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : AIK2 antibody; AIM-1 antibody; AIM1 antibody; ARK-2 antibody; ARK2 antibody; AurB antibody; AURKB antibody; AURKB_HUMAN antibody; Aurora 1 antibody; Aurora and Ipl1 like midbody associated protein 1 antibody; Aurora kinase B antibody; Aurora related kinase 2 antibody; Aurora- and Ipl1-like midbody-associated protein 1 antibody; Aurora-B antibody; Aurora-related kinase 2 antibody; Aurora/IPL1 related kinase 2 antibody; Aurora/IPL1-related kinase 2 antibody; IPL1 antibody; PPP1R48 antibody; Protein phosphatase 1 reg µLatory subunit 48 antibody; Serine/theronine kinase 12 antibody; Serine/threonine protein kinase 12 antibody; Serine/threonine-protein kinase 12 antibody; Serine/threonine-protein kinase aurora-B antibody; STK-1 antibody; STK1 antibody; STK12 antibody; STK5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96GD4
Immunogen : Recombinant Human Aurora kinase B protein (1-255AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key reg µLator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtub µLe stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtub µLes to kinetochores and is a key reg µLator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercell µLar chromosome bridges and accum µLation of DNA damage : phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed : 22422861 PubMed : 24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1 SEPT1 VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at \'Ser-10\' and \'Ser-28\' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively reg µLates its transcriptional activity. Key reg µLator of active promoters in resting B- and T-lymphocytes : acts by mediating phosphorylation of H3S28ph at active promoters in resting B-cells, inhibiting RNF2/RING1B-mediated ubiquitination of histone H2A and enhancing binding and activity of the USP16 deubiquitinase at transcribed genes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKB
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AIK antibody; ARK-1 antibody; ARK1 antibody; AURA antibody; Aurka antibody; Aurora 2 antibody; Aurora A antibody; Aurora kinase A antibody; Aurora-related kinase 1 antibody; Aurora/IPL1 like kinase antibody; AURORA/IPL1-like kinase antibody; Aurora/IPL1-related kinase 1 antibody; AURORA2 antibody; Breast tumor-amplified kinase antibody; BTAK antibody; hARK1 antibody; IAK antibody; IPL1 related kinase antibody; MGC34538 antibody; OTTHUMP00000031340 antibody; OTTHUMP00000031341 antibody; OTTHUMP00000031342 antibody; OTTHUMP00000031343 antibody; OTTHUMP00000031344 antibody; OTTHUMP00000031345 antibody; OTTHUMP00000166071 antibody; OTTHUMP00000166072 antibody; PPP1R47 antibody; Protein phosphatase 1 reg µLatory subunit 47 antibody; Serine/threonine kinase 15 antibody; Serine/threonine kinase 6 antibody; Serine/threonine protein kinase 15 antibody; Serine/threonine-protein kinase 15 antibody; Serine/threonine-protein kinase 6 antibody; Serine/threonine-protein kinase aurora-A antibody; STK15 antibody; STK6 antibody; STK6_HUMAN antibody; STK7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14965
Immunogen : Recombinant Human Aurora kinase A protein (1-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Mitotic serine/threonine kinases that contributes to the reg µLation of cell cycle progression. Associates with the centrosome and the spindle microtub µLes during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1 CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1 PARD3, PPP1R2, PLK1 RASSF1 TACC3, p53/TP53 and TPX2. Reg µLates KIF2A tub µLin depolymerase activity. Required for normal axon formation. Plays a role in microtub µLe remodeling during neurite extension. Important for microtub µLe formation and/or stabilization. Also acts as a key reg µLatory component of the p53/TP53 pathway, and partic µLarly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKA
Research Areas : Cancer; Cell biology; Signal transduction