FITC

Volume : 50 µg
Clone Number :
Aliases : AT7L3_HUMAN antibody; Ataxin 7 like 3 antibody; Ataxin 7 like protein 3 antibody; Ataxin-7-like protein 3 antibody; atxn7l3 antibody; SAGA associated factor 11 homolog antibody; SAGA-associated factor 11 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14CW9
Immunogen : Recombinant Human Ataxin-7-like protein 3 protein (51-347AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the transcription reg µLatory histone acetylation (HAT) complex SAGA, a m µLtiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN7L3
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 2810423G08Rik antibody; AT7L1_HUMAN antibody; Ataxin 7 like 4 antibody; Ataxin 7 like protein 1 antibody; ataxin 7-like 1 antibody; Ataxin-7-like protein 1 antibody; Ataxin-7-like protein 4 antibody; ATXN7L1 antibody; Atxn7l4 antibody; FLJ40255 antibody; FLJ58242 antibody; KIAA1218 antibody; mCG_142289 antibody; MGC10760 antibody; MGC28883 antibody; MGC33190 antibody; RGD1564242 antibody; tcag7.1150 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLK2
Immunogen : Recombinant Human Ataxin-7-like protein 1 protein (1-146AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN7L1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : ATXN7 antibody; SCA7Ataxin-7 antibody; Spinocerebellar ataxia type 7 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15265
Immunogen : Recombinant Human Ataxin-7 protein (402-503AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtub µLe cytoskeleton stabilization.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN7
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : AT3 antibody; Ataxin 3 antibody; ataxin 3 variant h antibody; ataxin 3 variant m antibody; ataxin 3 variant ref antibody; Ataxin-3 antibody; ATX3 antibody; ATX3_HUMAN antibody; ATXN3 antibody; EC 3.4.22. antibody; JOS antibody; Josephin antibody; Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) antibody; Machado Joseph disease antibody; Machado Joseph disease protein 1 antibody; Machado-Joseph disease protein 1 antibody; Machado-Joseph disease protein 1 homolog antibody; MJD antibody; MJD gene antibody; MJD1 antibody; Olivopontocerebellar ataxia 3 antibody; OTTHUMP00000221583 antibody; OTTHUMP00000221585 antibody; OTTHUMP00000221586 antibody; OTTHUMP00000221587 antibody; OTTHUMP00000231995 antibody; OTTHUMP00000231997 antibody; Rsca3 antibody; SCA3 antibody; SCA3 gene antibody; Spinocerebellar ataxia type 3 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54252
Immunogen : Recombinant Human Ataxin-3 protein (1-288AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton reg µLation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP : recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key reg µLators of transcription and represses transcription : acts as a histone-binding protein that reg µLates transcription.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 50 µg
Clone Number :
Aliases : ASL13 antibody; Ataxin 2 antibody; Ataxin-2 antibody; ATX2_HUMAN antibody; Atxn2 antibody; Olivopontocerebellar ataxia 2; autosomal dominant antibody; SCA2 antibody; Spinocerebellar ataxia type 2 protein antibody; TNRC13 antibody; Trinucleotide repeat containing 13 antibody; Trinucleotide repeat containing gene 13 protein antibody; Trinucleotide repeat-containing gene 13 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99700
Immunogen : Recombinant Human Ataxin-2 protein (174-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in EGFR trafficking, acting as negative reg µLator of endocytic EGFR internalization at the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : ATXN1L antibody; BOAT antibody; BOAT1Ataxin-1-like antibody; Brother of ataxin-1 antibody; Brother of ATXN1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P0C7T5
Immunogen : Recombinant Human Ataxin-1-like protein (183-463AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Chromatin-binding factor that repress Notch signaling in the absence of Notch intracell µLar domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN1L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Alpha thalassemia/mental retardation syndrome X linked homolog antibody; ATP dependent helicase ATRX antibody; ATP-dependent helicase ATRX antibody; ATR2 antibody; Atrx antibody; ATRX_HUMAN antibody; DNA dependent ATPase and helicase antibody; Helicase 2; X linked antibody; MGC2094 antibody; MRXHF1 antibody; RAD54 antibody; RAD54L antibody; SFM1 antibody; SHS antibody; Transcriptional reg µLator ATRX antibody; X linked helicase II antibody; X linked nuclear protein antibody; X-linked helicase II antibody; X-linked nuclear protein antibody; XH2 antibody; XNP antibody; Znf HX antibody; Znf-HX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P46100
Immunogen : Recombinant Human Transcriptional reg µLator ATRX protein (2161-2443AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in transcriptional reg µLation and chromatin remodeling. Facilitates DNA replication in m µLtiple cell µLar environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into reg µLar chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX : DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. Its heterochromatin targeting is proposed to involve a combinatorial readout of histone H3 modifications (specifically methylation states of H3K9 and H3K4) and association with CBX5. Involved in maintaining telomere structural integrity in embryonic stem cells which probably implies recruitment of CBX5 to telomers. Reports on the involvement in transcriptional reg µLation of telomeric repeat-containing RNA (TERRA) are conflicting; according to a report, it is not sufficient to decrease chromatin condensation at telomers nor to increase expression of telomeric RNA in fibroblasts (PubMed : 24500201). May be involved in telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines. Acts as negative reg µLator of chromatin incorporation of transcriptionally repressive histone H2AFY, partic µLarily at telomeres and the alpha-globin cluster in erythroleukemic cells. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, required for the chromatin occupancy of SMC1 and CTCTF within the H19 imprinting control region (ICR) and involved in esatblishment of histone tails modifications in the ICR. May be involved in brain development and facial morphogenesis. Binds to zinc-finger coding genes with atypical chromatin signatures and reg µLates its H3K9me3 levels. Forms a complex with ZNF274, TRIM28 and SETDB1 to facilitate the deposition and maintenance of H3K9me3 at the 3\' exons of zinc-finger genes (PubMed : 27029610).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATRX
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Ataxia telangiectasia and Rad3 related antibody; Ataxia telangiectasia and Rad3-related protein antibody; ATR antibody; ATR_HUMAN antibody; FCTCS antibody; FRAP Related Protein 1 antibody; FRAP-related protein 1 antibody; FRP1 antibody; MEC1 antibody; MEC1 mitosis entry checkpoint 1 homolog antibody; Protein kinase ATR antibody; RAC3 antibody; Rad3 related protein antibody; SCKL antibody; SCKL1 antibody; Serine/threonine protein kinase ATR antibody; Serine/threonine-protein kinase ATR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13535
Immunogen : Recombinant Human Serine/threonine-protein kinase ATR protein (2405-2644AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), µLtraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1 CHEK1 MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates \\\'Ser-139\\\' of histone variant H2AX/H2AFX at sites of DNA damage, thereby reg µLating DNA damage response mechanism. Required for FANCD2 ubiquitination. Critical for maintenance of fragile site stability and efficient reg µLation of centrosome duplication.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATR
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : atpE antibody; Clos_2565 antibody; ATP synthase subunit c antibody; ATP synthase F(0) sector subunit c antibody; F-type ATPase subunit c antibody; F-ATPase subunit c antibody; Lipid-binding protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs))
UniProt ID : A8MJW4
Immunogen : Recombinant strain OhILAs ATP synthase subunit c protein (1-88AA)
Raised in : Rabbit
Species Reactivity : strain OhILAs
Tested Applications :
Background : F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : atpE
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : atpBATP synthase subunit beta antibody; chloroplastic antibody; EC 7.1.2.2 antibody; ATP synthase F1 sector subunit beta antibody; F-ATPase subunit beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Lemna minor (Common duckweed)
UniProt ID : A9L9A3
Immunogen : Recombinant Lemna minor ATP synthase subunit beta, chloroplastic protein (1-497AA)
Raised in : Rabbit
Species Reactivity : Lemna minor
Tested Applications :
Background : Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : atpB
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ATPAF2 antibody; ATP12 antibody; LP3663ATP synthase mitochondrial F1 complex assembly factor 2 antibody; ATP12 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N5M1
Immunogen : Recombinant Human ATP synthase mitochondrial F1 complex assembly factor 2 protein (41-289AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATPAF2
Research Areas : Cancer; Metabolism; Signal transduction