FITC

Volume : 50 µg
Clone Number :
Aliases : groL antibody; groEL antibody; mopA antibody; CPn_0134 antibody; CP_0638 antibody; CpB013560 kDa chaperonin antibody; GroEL protein antibody; Protein Cpn60 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Chlamydia pneumoniae (Chlamydophila pneumoniae)
UniProt ID : P31681
Immunogen : Recombinant Chlamydia pneumoniae 60 kDa chaperonin protein (1-214AA)
Raised in : Rabbit
Species Reactivity : Chlamydia pneumoniae
Tested Applications :
Background : Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : groL
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CSNB1B antibody; DKFZp686H1993 antibody; GluR6 antibody; Glutamate receptor metabotropic 6 antibody; GPRC1F antibody; Grm6 antibody; GRM6_HUMAN antibody; Metabotropic glutamate receptor 6 antibody; mGlu6 antibody; mGluR6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15303
Immunogen : Recombinant Human Metabotropic glutamate receptor 6 protein (370-531AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and mod µLates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stim µLates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRM6
Research Areas : Neuroscience; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : GLUR3 antibody; Glutamate metabotropic receptor 3 antibody; Glutamate receptor metabotropic 3 antibody; GPRC1C antibody; GRM3 antibody; GRM3_HUMAN antibody; Metabotropic glutamate receptor 3 antibody; MGlu3 antibody; mGluR3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14832
Immunogen : Recombinant Human Metabotropic glutamate receptor 3 protein (46-354AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and mod µLates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRM3
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AMPA selective glutamate receptor 2 antibody; GLUR2 antibody; GLURB antibody; Glutamate metabotropic receptor 2 antibody; Glutamate receptor homolog antibody; Glutamate receptor metabotropic 2 antibody; GPRC1B antibody; GRM2 antibody; GRM2_HUMAN antibody; Metabotropic glutamate receptor 2 antibody; mGlu2 antibody; mGluR2 antibody; OTTHUMP00000210984 antibody; OTTHUMP00000210986 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14416
Immunogen : Recombinant Human Metabotropic glutamate receptor 2 protein (93-221AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and mod µLates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRM2
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : Glutamate receptor metabotropic 1 antibody; glutamate receptor; metabotropic 1 antibody; GPRC1A antibody; GRM1 antibody; GRM1-Alpha antibody; GRM1_HUMAN antibody; GRM1A antibody; Metabotropic glutamate receptor 1 antibody; mGlu1 antibody; mGluR1 antibody; MGLUR1-Alpha antibody; MGLUR1A antibody; SCAR13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13255
Immunogen : Recombinant Human Metabotropic glutamate receptor 1 protein (880-1017AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and mod µLates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRM1
Research Areas : Neuroscience

Volume : 50 µL
Clone Number :
Aliases : GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WTQ7
Immunogen : Recombinant Human Rhodopsin kinase protein (342-550AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRK7
Research Areas : Signal Transduction

Volume : 50 µL
Clone Number :
Aliases : GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WTQ7
Immunogen : Recombinant Human Rhodopsin kinase protein (342-550AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRK7
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ39780 antibody; FP2025 antibody; G protein coupled receptor kinase 5 antibody; G protein coupled receptor kinase GRK5 antibody; G protein-coupled receptor kinase 5 antibody; G protein-coupled receptor kinase GRK5 antibody; GPRK5 antibody; GRK-pan antibody; GRK5 antibody; GRK5_HUMAN antibody; Pan-GRK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P34947
Immunogen : Recombinant Human G protein-coupled receptor kinase 5 protein (406-590AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-reg µLation. Phosphorylates a variety of GPCRs, including adrenergic receptors, muscarinic acetylcholine receptors (more specifically Gi-coupled M2/M4 subtypes), dopamine receptors and opioid receptors. In addition to GPCRs, also phosphorylates various substrates : Hsc70-interacting protein/ST13, TP53/p53, HDAC5, and arrestin-1/ARRB1. Phosphorylation of ARRB1 by GRK5 inhibits G-protein independent MAPK1/MAPK3 signaling downstream of 5HT4-receptors. Phosphorylation of HDAC5, a repressor of myocyte enhancer factor 2 (MEF2) leading to nuclear export of HDAC5 and allowing MEF2-mediated transcription. Phosphorylation of TP53/p53, a crucial tumor suppressor, inhibits TP53/p53-mediated apoptosis. Phosphorylation of ST13 reg µLates internalization of the chemokine receptor. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRK5
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : G protein coupled receptor kinase 4 antibody; G protein-coupled receptor kinase 2 (Drosophila)-like antibody; G protein-coupled receptor kinase 4 antibody; G protein-coupled receptor kinase GRK4 antibody; G proteinm coupled receptor kinase GRK4 antibody; GPRK2L antibody; GPRK4 antibody; GRK4 antibody; GRK4_HUMAN antibody; GRK4a antibody; ITI1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P32298
Immunogen : Recombinant Human G protein-coupled receptor kinase 4 protein (1-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmod µLin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmod µLin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRK4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ADRBK2 antibody; Adrenergic; beta; receptor kinase 2 antibody; ARBK2_HUMAN antibody; BARK2 antibody; Beta adrenergic receptor kinase 2 antibody; Beta ARK 2 antibody; Beta-adrenergic receptor kinase 2 antibody; Beta-ARK-2 antibody; EC 2.7.11.15 antibody; G protein coupled receptor kinase 3 antibody; G-protein-coupled receptor kinase 3 antibody; GRK3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35626
Immunogen : Recombinant Human Beta-adrenergic receptor kinase 2 protein (343-480AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRK3
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ADRBK1 antibody; Adrenergic beta receptor kinase 1 antibody; ARBK1_HUMAN antibody; BARK antibody; BARK1 antibody; Beta adrenergic receptor kinase 1 antibody; Beta ARK 1 antibody; Beta ARK1 antibody; Beta-adrenergic receptor kinase 1 antibody; Beta-ARK-1 antibody; FLJ16718 antibody; G protein coupled receptor kinase 2 antibody; G-protein coupled receptor kinase 2 antibody; GRK2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P25098
Immunogen : Recombinant Human Beta-adrenergic receptor kinase 1 protein (2-221AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key reg µLator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GRK2
Research Areas : Neuroscience; Signal transduction