FITC

Volume : 50 µg
Clone Number :
Aliases : HMGCLL1 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase antibody; cytoplasmic antibody; EC 4.1.3.4 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 antibody; Endoplasmic retic µLum 3-hydroxy-3-methylglutaryl-CoA lyase antibody; er-cHL antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TB92
Immunogen : Recombinant Human 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic protein (2-340AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCLL1
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase), HMGCL
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35914
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial protein (28-325aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as reg µLators of metabolism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCL
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : HMGB4 antibody; High mobility group protein B4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WW32
Immunogen : Recombinant Human High mobility group protein B4 protein (1-186AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : chromosomal protein; Nonhistone; HMG4 antibody; High mobility group (nonhistone chromosomal) protein 4 antibody; High mobility group box 3 antibody; High mobility group protein 2a antibody; High mobility group protein 4 antibody; High mobility group protein B3 antibody; High mobility group protein HMG4 antibody; HMG 4 antibody; HMG-2a antibody; HMG-4 antibody; HMG2A antibody; HMGB 3 antibody; Hmgb3 antibody; HMGB3_HUMAN antibody; MGC90319 antibody; Non histone chromosomal protein antibody; Nonhistone chromosomal protein HMG4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15347
Immunogen : Recombinant Human High mobility group protein B3 protein (1-103AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively reg µLates B-cell and myeloid cell differentiation. In hematopoietic stem cells may reg µLate the balance between self-renewal and differentiation. Involved in negative reg µLation of canonical Wnt signaling (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : C80539 antibody; High mobility group (nonhistone chromosomal) protein 2 antibody; High mobility group box 2 antibody; High mobility group protein 2 antibody; High mobility group protein B2 antibody; HMG 2 antibody; HMG B2 antibody; HMG-2 antibody; HMG2 antibody; HMGB2 antibody; HMGB2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26583
Immunogen : Recombinant Human High mobility group protein B2 protein (43-185AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant reg µLatory sequences into close proximity (PubMed : 7797075, PubMed : 11909973, PubMed : 19522541 PubMed : 18413230, PubMed : 19965638, PubMed : 20123072). Involved in V(D)J recombination by acting as a cofactor of the RAG complex : acts by stim µLating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a promiscuous immunogenic DNA/RNA sensor which cooperates with subsequent discriminative sensing by specific pattern recognition receptors (By similarity). In the extracell µLar compartment acts as a chemokine. Promotes proliferation and migration of endothelial cells implicating AGER/RAGE (PubMed : 19811285). Has antimicrobial activity in gastrointestinal epithelial tissues (PubMed : 23877675). Involved in inflammatory response to antigenic stim µLus coupled with proinflammatory activity (By similarity). Involved in mod µLation of neurogenesis probably by reg µLation of neural stem proliferation (By similarity). Involved in artic µLar cartilage surface maintenance implicating LEF1 and the Wnt/beta-catenin pathway (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility group protein 1) (HMG-1), Hmgb1 Hmg-1 Hmg1
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P63159
Immunogen : Recombinant Rat High mobility group protein B1 protein (2-18aa)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications :
Background : M µLtifunctional redox sensitive protein with various roles in different cell µLar compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molec µLar pattern (DAMP) molec µLe that amplifies immune responses during tissue injury. Released to the extracell µLar environment can bind DNA, nucleosomes, IL-1 beta, CXCL12, AGER isoform 2/sRAGE, lipopolysaccharide (LPS) and lipoteichoic acid (LTA), and activates cells thro µgh engagement of m µLtiple surface receptors. In the extracell µLar compartment f µLly reduced HMGB1 (released by necrosis) acts as a chemokine, dis µLfide HMGB1 (actively secreted) as a cytokine, and s µLfonyl HMGB1 (released from apoptotic cells) promotes immunological tolerance (PubMed : 23519706, PubMed : 23446148, PubMed : 23994764, PubMed : 25048472). Has proangiogenic activity. May be involved in platelet activation. Binds to phosphatidylserine and phosphatidylethanolamide (PubMed : 11154118). Bound to RAGE mediates signaling for neuronal outgrowth (PubMed : 1885601 PubMed : 2461949, PubMed : 7592757, PubMed : 12183440). May play a role in accum µLation of expanded polyglutamine (polyQ) proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Hmgb1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : HEM3_HUMAN antibody; HMBS antibody; Hydroxymethylbilane synthase antibody; PBG D antibody; PBG-D antibody; PBGD antibody; PORC antibody; Porphobilinogen deaminase antibody; porphyria, acute, Chester type antibody; Pre uroporphyrinogen synthase antibody; Pre-uroporphyrinogen synthase antibody; UPS antibody; Uroporphyrinogen I synthase antibody; Uroporphyrinogen I synthetase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08397
Immunogen : Recombinant Human Porphobilinogen deaminase protein (283-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMBS
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dJ324O17.1 antibody; H13 antibody; hIMP1 antibody; Histocompatibility (minor) 13 antibody; HM13 antibody; HM13_HUMAN antibody; IMP-1 antibody; IMP1 antibody; IMPAS antibody; IMPAS-1 antibody; Intramembrane protease 1 antibody; Intramembrane protease antibody; Minor histocompatibility antigen 13 antibody; Minor histocompatibility antigen H13 antibody; MSTP086 antibody; OTTHUMP00000030527 antibody; OTTHUMP00000030528 antibody; OTTHUMP00000030530 antibody; OTTHUMP00000214528 antibody; Presenilin-like protein 3 antibody; PSENL3 antibody; PSL3 antibody; Signal peptide peptidase antibody; Signal peptide peptidase beta antibody; SPP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TCT9
Immunogen : Recombinant Human Minor histocompatibility antigen H13 protein (336-377AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, res µLting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed : 11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed : 12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed : 12077416, PubMed : 11714810, PubMed : 14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed : 25239945). May play a role in graft rejection (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HM13
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : hly antibody; hla antibody; SAOUHSC_01121Alpha-hemolysin antibody; Alpha-HL antibody; Alpha-toxin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain NCTC 8325)
UniProt ID : Q2G1X0
Immunogen : Recombinant Staphylococcus aureus Alpha-hemolysin protein (27-319AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications :
Background : Alpha-toxin binds to the membrane of eukaryotic cells res µLting in the release of low-molec µLar weight molec µLes and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hly
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DNA-binding protein/plasminogen activator inhibitor 1 reg µLator antibody; Helicase like transcription factor antibody; Helicase-like transcription factor antibody; HIP116 antibody; HIP116A antibody; HLTF 1 antibody; Hltf antibody; HLTF_HUMAN antibody; HLTF1 antibody; p113 antibody; RING finger protein 80 antibody; RNF80 antibody; SMARC A3 antibody; SMARCA 3 antibody; SMARCA3 antibody; SNF2-like 3 antibody; SNF2L3 antibody; Sucrose nonfermenting protein 2 like 3 antibody; Sucrose nonfermenting protein 2-like 3 antibody; SWI/SNF related matrix associated actin dependent reg µLator of chromatin subfamily A member 3 antibody; SWI/SNF-related matrix-associated actin-dependent reg µLator of chromatin a3 antibody; SWI/SNF-related matrix-associated actin-dependent reg µLator of chromatin subfamily A member 3 antibody; ZBU 1 antibody; ZBU1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14527
Immunogen : Recombinant Human Helicase-like transcription factor protein (332-476AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability thro µgh acting as a ubiquitin ligase for \'Lys-63\'-linked polyubiquitination of chromatin-bound PCNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLTF
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : hlgC antibody; SAR2510 antibody; Gamma-hemolysin component C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain MRSA252)
UniProt ID : Q6GE13
Immunogen : Recombinant Staphylococcus aureus Gamma-hemolysin component C protein (30-315AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications :
Background : Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hlgC
Research Areas : Others