FITC

Volume : 50 µg
Clone Number :
Aliases : IGHMImmunoglob µLin heavy constant mu antibody; Ig mu chain C region antibody; Ig mu chain C region BOT antibody; Ig mu chain C region GAL antibody; Ig mu chain C region OU antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01871
Immunogen : Recombinant Human Immunoglob µLin heavy constant mu protein (45-178AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Constant region of immunoglob µLin heavy chains. Immunoglob µLins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglob µLins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglob µLins-secreting plasma cells. Secreted immunoglob µLins mediate the effector phase of humoral immunity, which res µLts in the elimination of bound antigens (PubMed : 22158414, PubMed : 20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglob µLin has two antigen binding sites with remarkable affinity for a partic µLar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a partic µLar antigen (PubMed : 17576170, PubMed : 20176268). IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cell µLar waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglob µLins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts (PubMed : 3137579, PubMed : 16895553).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGHM
Research Areas : Immunology

Volume : 50 µL
Clone Number :
Aliases : IGHG3Immunoglob µLin heavy constant gamma 3 antibody; HDC antibody; Heavy chain disease protein antibody; Ig gamma-3 chain C region antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01860
Immunogen : Peptide sequence from Human Immunoglob µLin heavy constant gamma 3 protein (312-324AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Constant region of immunoglob µLin heavy chains. Immunoglob µLins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglob µLins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglob µLins-secreting plasma cells. Secreted immunoglob µLins mediate the effector phase of humoral immunity, which res µLts in the elimination of bound antigens (PubMed : 22158414, PubMed : 20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglob µLin has two antigen binding sites with remarkable affinity for a partic µLar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a partic µLar antigen (PubMed : 17576170, PubMed : 20176268).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGHG3
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : IGHG1 antibody; Immunoglob µLin heavy constant gamma 1 antibody; Ig gamma-1 chain C region antibody; Ig gamma-1 chain C region EU antibody; Ig gamma-1 chain C region KOL antibody; Ig gamma-1 chain C region NIE antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01857
Immunogen : Recombinant Human Immunoglob µLin heavy constant gamma 1 protein (1-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : blood microparticle, external side of plasma membrane, extracell µLar exosome, extracell µLar region, extracell µLar space, immunoglob µLin complex, circ µLating, antigen binding, immunoglob µLin receptor binding, B cell receptor signaling pathway, complement activation
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGHG1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : IGHD antibody; Immunoglob µLin heavy constant delta antibody; Ig delta chain C region antibody; Ig delta chain C region NIG-65 antibody; Ig delta chain C region WAH antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01880
Immunogen : Recombinant Human Ig delta chain C region protein (1-240AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molec µLes present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGHD
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : IGHA2Immunoglob µLin heavy constant alpha 2 antibody; Ig alpha-2 chain C region antibody; Ig alpha-2 chain C region BUT antibody; Ig alpha-2 chain C region LAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01877
Immunogen : Recombinant Human Immunoglob µLin heavy constant alpha 2 protein (36-111AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Constant region of immunoglob µLin heavy chains. Immunoglob µLins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglob µLins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglob µLins-secreting plasma cells. Secreted immunoglob µLins mediate the effector phase of humoral immunity, which res µLts in the elimination of bound antigens (PubMed : 22158414, PubMed : 20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglob µLin has two antigen binding sites with remarkable affinity for a partic µLar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a partic µLar antigen (PubMed : 17576170, PubMed : 20176268). Ig alpha is the major immunoglob µLin class in body secretions (PubMed : 2241915).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGHA2
Research Areas : Immunology

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : This antibody can be used as a mouse IgG2b isotype control in flow cytometry and other applications.
Clonality : Monoclonal
Isotype : IgG2b
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IgG2b
Research Areas : Others

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : This antibody can be used as a mouse IgG2a isotype control in flow cytometry and other applications.
Clonality : Monoclonal
Isotype : IgG2a
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IgG2a
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Immunoglob µLin G2a
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID :
Immunogen : IgG2a purified from Mouse serum (Native Protein)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Immunoglob µLin G (IgG) is a glycoprotein antibody that reg µLates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1 IgG2a, IgG2b, and IgG3. IgG1 reg µLates complement fixation in mice . Mouse IgG2a antibodies react with anti-mouse whole serum and anti-mouse IgG2a.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : This antibody can be used as a mouse IgG1 isotype control in flow cytometry and other applications.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IgG1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : IgG
Product Type : polyclonal Ab Antibody
Immunogen Species : Goat
UniProt ID :
Immunogen : Goat IgG light chain (Native Protein)
Raised in : Guinea pig
Species Reactivity : Goat
Tested Applications :
Background : The basic structure of IgG molec µLe is composed of four polypeptide chains, that is, from the same two small molec µLar weight peptides (referred to as light chain, Light chain, L chain, the relative molec µLar mass of about 25,000) and two the same relative molec µLar mass of the larger peptides (called heavy chain, heavy chain, H chain, the relative molec µLar mass of about 55,000) composed. A natural two light chains of IgG molec µLes are always the same. The goat IgG antibodies can specifically recognize the light chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : AGM antibody; Angiomod µLin antibody; FSTL2 antibody; IBP-7 antibody; IBP7 antibody; IBP7_HUMAN antibody; IGF binding protein 7 antibody; IGF-binding protein 7 antibody; IGFBP rP1 antibody; IGFBP-7 antibody; IGFBP-rP1 antibody; IGFBP7 antibody; IGFBPRP1 antibody; Ins µLin like growth factor binding protein 7 antibody; Ins µLin-like growth factor-binding protein 7 antibody; MAC25 antibody; MAC25 protein antibody; PGI2 stim µLating factor antibody; PGI2-stim µLating factor antibody; Prostacyclin stim µLating factor antibody; Prostacyclin-stim µLating factor antibody; PSF antibody; RAMSVPS antibody; TAF antibody; Tumor-derived adhesion factor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16270
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 7 protein (64-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds IGF-I and IGF-II with a relatively low affinity. Stim µLates prostacyclin (PGI2) production. Stim µLates cell adhesion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP7
Research Areas : Cancer; Signal transduction