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AGO2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Ago 2 antibody; AGO2_HUMAN antibody; Argonaute 2 antibody; argonaute 2; RISC catalytic component antibody; Argonaute RISC catalytic component 2 antibody; Argonaute2 antibody; CTA-204B4.6 antibody; dAgo2 antibody; eIF 2C 2 antibody; eIF-2C 2 antibody; eIF2C 2 antibody; Eif2c2 antibody; Eukaryotic translation initiation factor 2C 2 antibody; Eukaryotic translation initiation factor 2C subunit 2 antibody; hAgo2 antibody; MGC3183 antibody; PAZ Piwi domain protein antibody; PPD antibody; Protein argonaute-2 antibody; Protein slicer antibody; Q10 antibody; Slicer protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKV8
Immunogen : Recombinant Human Protein argonaute-2 protein (517-818AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The minimal RISC appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally res µLts in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA res µLts in silencing thro µgh inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accum µLation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3-UTR). Can also up-reg µLate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3-UTR of the TNF (TNF-alpha) mRNA and up-reg µLates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGO2
Research Areas : Epigenetics and Nuclear Signaling
0.01 0.01 USD
AGO2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AGO2
GeneID : 27161
Uniprot : Q9UKV8
Specificity : AGO2 Antibody detects endogenous levels of total AGO2.
Immunogen : A syntheVolumed peptide derived from human AGO2, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Xenopus
Application : WB,IHC
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200
Conj µgate : Unconj µgated
RRID : AB_2845051
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12246-BP
Des# Blocking Peptide : AGO2 Blocking peptide
Blocking Peptide Price : $549 CAD
0.01 0.01 USD
AGO1 Antibody HRP conjugated
Volume : 50 µL
Clone Number :
Aliases : AGO1 antibody; AGO1_HUMAN antibody; Argonaute 1 antibody; Argonaute 1 RISC catalytic component antibody; Argonaute1 antibody; eIF 2C 1 antibody; eIF-2C 1 antibody; eIF2C 1 antibody; EIF2C antibody; Eif2c1 antibody; Eukaryotic translation initiation factor 2C 1 antibody; GERP95 antibody; Golgi Endoplasmic Retic µLum protein 95 kDa antibody; hAgo1 antibody; Protein argonaute 1 antibody; Protein argonaute-1 antibody; Putative RNA binding protein Q99 antibody; Putative RNA-binding protein Q99 antibody; Q99 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µL18
Immunogen : Recombinant Human Protein argonaute-1 protein (251-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGO1
Research Areas : Signal Transduction
0.01 0.01 USD
AGO1 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : AGO1 antibody; AGO1_HUMAN antibody; Argonaute 1 antibody; Argonaute 1 RISC catalytic component antibody; Argonaute1 antibody; eIF 2C 1 antibody; eIF-2C 1 antibody; eIF2C 1 antibody; EIF2C antibody; Eif2c1 antibody; Eukaryotic translation initiation factor 2C 1 antibody; GERP95 antibody; Golgi Endoplasmic Retic µLum protein 95 kDa antibody; hAgo1 antibody; Protein argonaute 1 antibody; Protein argonaute-1 antibody; Putative RNA binding protein Q99 antibody; Putative RNA-binding protein Q99 antibody; Q99 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µL18
Immunogen : Recombinant Human Protein argonaute-1 protein (251-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGO1
Research Areas : Signal Transduction
0.01 0.01 USD
AGO1 Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : AGO1 antibody; AGO1_HUMAN antibody; Argonaute 1 antibody; Argonaute 1 RISC catalytic component antibody; Argonaute1 antibody; eIF 2C 1 antibody; eIF-2C 1 antibody; eIF2C 1 antibody; EIF2C antibody; Eif2c1 antibody; Eukaryotic translation initiation factor 2C 1 antibody; GERP95 antibody; Golgi Endoplasmic Retic µLum protein 95 kDa antibody; hAgo1 antibody; Protein argonaute 1 antibody; Protein argonaute-1 antibody; Putative RNA binding protein Q99 antibody; Putative RNA-binding protein Q99 antibody; Q99 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µL18
Immunogen : Recombinant Human Protein argonaute-1 protein (251-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGO1
Research Areas : Signal Transduction
0.01 0.01 USD
AGO1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AGO1
GeneID : 26523
Uniprot : Q9 µL18
Specificity : AGO1 Antibody detects endogenous levels of total AGO1.
Immunogen : A syntheVolumed peptide derived from human AGO1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841041
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7542-BP
Des# Blocking Peptide : AGO1 Blocking peptide
Blocking Peptide Price : $549 CAD
0.01 0.01 USD
aglB Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : aglB antibody; Probable alpha-galactosidase B antibody; EC 3.2.1.22 antibody; Melibiase B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Aspergillus niger
UniProt ID : Q9Y865
Immunogen : Recombinant Aspergillus niger Probable alpha-galactosidase B protein (21-443AA)
Raised in : Rabbit
Species Reactivity : Aspergillus niger
Tested Applications : ELISA
Background : Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molec µLes such as oligosaccharides and polysaccharides
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : aglB
Research Areas : Others
0.01 0.01 USD
aglB Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : aglB antibody; Probable alpha-galactosidase B antibody; EC 3.2.1.22 antibody; Melibiase B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Aspergillus niger
UniProt ID : Q9Y865
Immunogen : Recombinant Aspergillus niger Probable alpha-galactosidase B protein (21-443AA)
Raised in : Rabbit
Species Reactivity : Aspergillus niger
Tested Applications :
Background : Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molec µLes such as oligosaccharides and polysaccharides
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : aglB
Research Areas : Others
0.01 0.01 USD
aglB Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : aglB antibody; Probable alpha-galactosidase B antibody; EC 3.2.1.22 antibody; Melibiase B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Aspergillus niger
UniProt ID : Q9Y865
Immunogen : Recombinant Aspergillus niger Probable alpha-galactosidase B protein (21-443AA)
Raised in : Rabbit
Species Reactivity : Aspergillus niger
Tested Applications : ELISA
Background : Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molec µLes such as oligosaccharides and polysaccharides
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : aglB
Research Areas : Others
0.01 0.01 USD
aglB Antibody
Volume : 50 µg
Clone Number :
Aliases : aglB antibody; Probable alpha-galactosidase B antibody; EC 3.2.1.22 antibody; Melibiase B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Aspergillus niger
UniProt ID : Q9Y865
Immunogen : Recombinant Aspergillus niger Probable alpha-galactosidase B protein (21-443AA)
Raised in : Rabbit
Species Reactivity : Aspergillus niger
Tested Applications : ELISA
Background : Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molec µLes such as oligosaccharides and polysaccharides
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : aglB
Research Areas : Others
0.01 0.01 USD
AGL Antibody HRP conjugated
Volume : 50 µL
Clone Number :
Aliases : 1110061O17Rik antibody; 4-1 antibody; 4-glucantransferase antibody; 6-glucosidase antibody; 9430004C13Rik antibody; 9630046L06Rik antibody; AGL antibody; AI850929 antibody; Amylo 1 6 glucosidase 4 alpha glucanotransferase antibody; Amylo-1 antibody; Amylo-alpha-1 antibody; C77197 antibody; Dextrin 6-alpha-D-glucosidase antibody; GDE antibody; GDE_HUMAN antibody; Glycogen debrancher antibody; Glycogen debranching enzyme antibody; Glycogen storage disease type III antibody; Oligo-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35573
Immunogen : Recombinant Human Glycogen debranching enzyme protein (1217-1378AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : M µLtifunctional enzyme acting as 14-alpha-D-glucan : 14-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-16-glucosidase in glycogen degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGL
Research Areas : Cancer; Metabolism; Signal transduction
0.01 0.01 USD