Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AGER
GeneID : 177
Uniprot : Q15109
Specificity : AGER/RAGE Antibody detects endogenous levels of total AGER/RAGE.
Immunogen : A syntheVolumed peptide derived from human AGER/RAGE, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837794
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF5309-BP
Des# Blocking Peptide : AGER/RAGE Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Protein Type : Target proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 50 µg
Clone Number :
Aliases : Advanced glycosylation end product-specific receptor antibody; Ager antibody; DAMA 358M23.4 antibody; MGC2235 antibody; MGC22357 antibody; RAGE_HUMAN antibody; Receptor for advanced glycation end products antibody; Receptor for advanced glycosylation end products antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15109
Immunogen : Recombinant Human Advanced glycosylation end product-specific receptor protein (23-342AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accum µLate in vasc µLar tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vasc µLar inflammation in conditions such as atherosclerosis and in partic µLar as a complication of diabetes. AGE/RAGE signaling plays an important role in reg µLating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cell µLar activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling By similarity. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracell µLar to the intracell µLar space in cortical neurons. ABPP-initiated RAGE signaling, especially stim µLation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGER
Research Areas : Neuroscience; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : Advanced glycosylation end product-specific receptor antibody; Ager antibody; DAMA 358M23.4 antibody; MGC2235 antibody; MGC22357 antibody; RAGE_HUMAN antibody; Receptor for advanced glycation end products antibody; Receptor for advanced glycosylation end products antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15109
Immunogen : Recombinant Human Advanced glycosylation end product-specific receptor protein (23-342AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accum µLate in vasc µLar tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vasc µLar inflammation in conditions such as atherosclerosis and in partic µLar as a complication of diabetes. AGE/RAGE signaling plays an important role in reg µLating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cell µLar activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling By similarity. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracell µLar to the intracell µLar space in cortical neurons. ABPP-initiated RAGE signaling, especially stim µLation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGER
Research Areas : Neuroscience; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : Advanced glycosylation end product-specific receptor antibody; Ager antibody; DAMA 358M23.4 antibody; MGC2235 antibody; MGC22357 antibody; RAGE_HUMAN antibody; Receptor for advanced glycation end products antibody; Receptor for advanced glycosylation end products antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15109
Immunogen : Recombinant Human Advanced glycosylation end product-specific receptor protein (23-342AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accum µLate in vasc µLar tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vasc µLar inflammation in conditions such as atherosclerosis and in partic µLar as a complication of diabetes. AGE/RAGE signaling plays an important role in reg µLating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cell µLar activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling By similarity. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracell µLar to the intracell µLar space in cortical neurons. ABPP-initiated RAGE signaling, especially stim µLation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGER
Research Areas : Neuroscience; Cardiovasc µLar

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Mediates interactions of advanced glycosylation end products(AGE). These are nonenzymatically glycosylated proteins which accum µLate in vasc µLar tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vasc µLar inflammation in conditions such as atherosclerosis and in partic µLar as a complication of diabetes. AGE/RAGE signaling plays an important role in reg µLating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cell µLar activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling(By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide(ABPP) across the cell membrane from the extracell µLar to the intracell µLar space in cortical neurons. ABPP-initiated RAGE signaling, especially stim µLation of p38 mitogen-activated protein kinase(MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
Immunogen : advanced glycosylation end product-specific receptor
Aliases : AGER, RAGE
Observed MW : 43 kDa
Uniprot ID : Q15109
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 200-1 : 2000; IHC : 1 : 20-1 : 200
Gene ID : 177
Research Area : Immunology, Signal Transduction, Developmental biology

Volume : 96 Test
Species : Universal
Uniprot ID :
Short name : AGE
Alias : AGE|Advanced glycation end-product
Sensitivity : 37.5ng/ml
Range : 62.5-4000ng/ml
Detection method : Competitive ELISA, Coated with Antigen
Storage_tempeRature : 2-8 °C for 6 months
Research Area : Signal Transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : ATP/GTP binding protein-like 5
Aliases : AGBL5, ATP/GTP binding protein like 5, CCP5, FLJ21839
Observed MW : 75 kDa
Uniprot ID : Q8NDL9
Reactivity : Human
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 60509
Research Area : Signal Transduction, Metabolism

Volume : 50 µL
Clone Number :
Aliases : AGBL5 antibody; ATP/GTP binding protein like 5 antibody; ATP/GTP-binding protein-like 5 antibody; CBPC5_HUMAN antibody; CCP5 antibody; Cytosolic carboxypeptidase like protein 5 antibody; Cytosolic carboxypeptidase-like protein 5 antibody; FLJ21839 antibody; Hypothetical protein FLJ21839 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NDL9
Immunogen : Fusion protein of Human AGBL5
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; ELISA : 1 : 2000-1 : 5000, IHC : 1 : 25-1 : 100
Background : Metallocarboxypeptidase that mediates tub µLin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tub µLins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/ CCP1 AGBL1/CCP4 and AGBL4/CCP6.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AGBL5
Research Areas : Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AGBL4
GeneID : 84871
Uniprot : Q5VU57
Specificity : AGBL4 Antibody detects endogenous levels of total AGBL4.
Immunogen : A syntheVolumed peptide derived from human AGBL4, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836341
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3981-BP
Des# Blocking Peptide : AGBL4 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tub µLins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tub µLin. Isoform 2 : Metallocarboxypeptidase that mediates tub µLin deglutamylation.
Immunogen : ATP/GTP binding protein-like 3
Aliases : AGBL3, ATP/GTP binding protein like 3, CBPC3, CCP3
Observed MW : 73 kDa
Uniprot ID : Q8NEM8
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 200-1 : 1000; IHC : 1 : 20-1 : 200
Gene ID : 340351
Research Area : Metabolism