Volume : 50 µg
Clone Number :
Aliases : Glutathione peroxidase 4 antibody; GPX 4 antibody; GPX-4 antibody; GPX4 antibody; GPX4_HUMAN antibody; GSHPx-4 antibody; MCSP antibody; mitochondrial antibody; PHGPx antibody; Phospholipid hydroperoxidase antibody; Phospholipid hydroperoxide glutathione peroxidase antibody; Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody; snGPx antibody; snPHGPx antibody; Sperm nucleus glutathione peroxidase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P36969
Immunogen : Recombinant Human Phospholipid hydroperoxide glutathione peroxidase, mitochondrial protein (74-197AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Co µLd play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death res µLting from an iron-dependent accum µLation of lipid reactive oxygen species, and by supporting T cell expansion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GPX4
Research Areas : Cancer; Metabolism; Signal transduction